caa a22 4500 467940037 CHVBK 20180406153009.0 cr unu---uuuuu 170328e20061201xx s 000 0 eng 10.1007/s00421-006-0306-6 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0306-6 Effects of two types of inactivity on the number of white blood cells in rats [Elektronische Daten] [Ken Shirato, Norio Motohashi, Jun Tanihata, Kaoru Tachiyashiki, Akio Tomoda, Kazuhiko Imaizumi] Prolonged inactivity is known to induce changes in responses of many physiological defense systems such as the hypothalamo-hypophyseal-adrenocortical axis, the sympathetic nervous system, and immuno-responsive systems. However, effects of various types of inactivity on immuno-responsive systems are still unknown. Therefore, the effects of two types of inactivity (immobilization: IMM and whole body suspension: WBS) on the number of white blood cells were studied in rats. Rats were divided into the control group and each inactivity group to compare the number of total white blood cells, lymphocytes, monocyte, neutrophil, eosinophil, and basophil during the experimental periods. Both IMM and WBS were maintained for 11days. IMM markedly increased the number of total white blood cells, monocyte, neutrophil, and eosinophil in the 1st to 10th day. However, the number of total white blood cells, monocyte, neutrophil, and eosinophil during the experiment of WBS were characterized by the presence of a lag phase followed by the significant increased actions. IMM did not change the number of basophil during the experimental period. However, WBS increased the number of basophil in the 1st to 8th day to 2.8-4.8 times, compared with the values of the control. Both IMM and WBS did not change the number of lymphocytes. From these results, WBS increases the number of natural immunity cells without changing acquired immunity cells, and there are different responses in the number of total white blood cells, monocyte, neutrophil, eosinophil, and basophil between IMM and WBS. Springer-Verlag, 2006 Inactivity nationallicence Immobilization nationallicence Whole body suspension nationallicence White blood cells nationallicence Immuno-responsive system nationallicence Shirato Ken Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut Motohashi Norio Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut Tanihata Jun Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut Tachiyashiki Kaoru Department of Living and Health Sciences, Joetsu University of Education, Yamayashiki, 943-8512, Joetsu, Japan aut Tomoda Akio Department of Biochemistry, Tokyo Medical University, 6-1-1, Shinjuku, 160-8402, Tokyo, Japan aut Imaizumi Kazuhiko Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut European Journal of Applied Physiology Springer-Verlag 98/6(2006-12-01), 590-600 1439-6319 98:6<590 2006 98 421 https://doi.org/10.1007/s00421-006-0306-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0306-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shirato Ken Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut NATIONALLICENCE 700 1- Motohashi Norio Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut NATIONALLICENCE 700 1- Tanihata Jun Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut NATIONALLICENCE 700 1- Tachiyashiki Kaoru Department of Living and Health Sciences, Joetsu University of Education, Yamayashiki, 943-8512, Joetsu, Japan aut NATIONALLICENCE 700 1- Tomoda Akio Department of Biochemistry, Tokyo Medical University, 6-1-1, Shinjuku, 160-8402, Tokyo, Japan aut NATIONALLICENCE 700 1- Imaizumi Kazuhiko Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, 359-1192, Tokorozawa, Japan aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/6(2006-12-01), 590-600 1439-6319 98:6<590 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer