caa a22 4500 467940096 CHVBK 20180406153009.0 cr unu---uuuuu 170328e20061001xx s 000 0 eng 10.1007/s00421-006-0273-y doi (NATIONALLICENCE)springer-10.1007/s00421-006-0273-y Response of antioxidant defences to oxidative stress induced by prolonged exercise: antioxidant enzyme gene expression in lymphocytes [Elektronische Daten] [Nuria Cases, Antoni Sureda, Isabel Maestre, Pedro Tauler, Antoni Aguiló, Alfredo Córdova, Enrique Roche, Josep Tur, Antoni Pons] The response of lymphocyte and plasma antioxidant defences to a prolonged exercise as a cycling stage in a professional race was analysed. Antioxidant enzyme activities and gene expression, carbonyl derivative and MDA levels were determined in lymphocytes. Plasma levels of vitamin E, carotenes, protein carbonyl derivatives and the test d-Roms were measured. Significant increases in plasmatic carbonyls and in the test d-Roms were observed after the cycling stage. No significant differences were found in the lymphocyte MDA and carbonyl derivative levels. A significant increase was found in plasma vitamin E concentration after the cycling stage; however, the lymphocyte vitamin E concentration did not change. Significant increases were observed in lymphocyte total superoxide dismutase (SOD) activity and in the levels of CuZn-SOD and Mn-SOD isoenzymes. The moderate levels of oxidative stress in the lymphocyte induced a cellular adaptation to exercise enough to counteract the negative effects of oxidative stress. Springer-Verlag, 2006 Cycling nationallicence Oxidative stress nationallicence Lymphocytes nationallicence Antioxidants nationallicence Cases Nuria Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut Sureda Antoni Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut Maestre Isabel Departamento de Biología Aplicada-Nutrición, Universidad Miguel Hernández, 03202, Alicante, Spain aut Tauler Pedro Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut Aguiló Antoni Laboratori de Ciències de l'Activitat Física, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut Córdova Alfredo Departamento de Fisiología y Bioquímica, Escuela Universitaria de Fisioterapia. Universidad de Valladolid, C/ Nicolás Rabal, 17, 42003, Soria, Spain aut Roche Enrique Departamento de Biología Aplicada-Nutrición, Universidad Miguel Hernández, 03202, Alicante, Spain aut Tur Josep Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut Pons Antoni Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut European Journal of Applied Physiology Springer-Verlag 98/3(2006-10-01), 263-269 1439-6319 98:3<263 2006 98 421 https://doi.org/10.1007/s00421-006-0273-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0273-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cases Nuria Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut NATIONALLICENCE 700 1- Sureda Antoni Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut NATIONALLICENCE 700 1- Maestre Isabel Departamento de Biología Aplicada-Nutrición, Universidad Miguel Hernández, 03202, Alicante, Spain aut NATIONALLICENCE 700 1- Tauler Pedro Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut NATIONALLICENCE 700 1- Aguiló Antoni Laboratori de Ciències de l'Activitat Física, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut NATIONALLICENCE 700 1- Córdova Alfredo Departamento de Fisiología y Bioquímica, Escuela Universitaria de Fisioterapia. Universidad de Valladolid, C/ Nicolás Rabal, 17, 42003, Soria, Spain aut NATIONALLICENCE 700 1- Roche Enrique Departamento de Biología Aplicada-Nutrición, Universidad Miguel Hernández, 03202, Alicante, Spain aut NATIONALLICENCE 700 1- Tur Josep Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut NATIONALLICENCE 700 1- Pons Antoni Departament de Biologia Fonamental i Ciències de la Salut, Edifici Guillem Colom, Universitat de les Illes Balears, Crta de Valldemossa, Km 7.5, 07122, Palma de Mallorca, Balears, Spain aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/3(2006-10-01), 263-269 1439-6319 98:3<263 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer