caa a22 4500 467940142 CHVBK 20180406153009.0 cr unu---uuuuu 170328e20061001xx s 000 0 eng 10.1007/s00421-006-0272-z doi (NATIONALLICENCE)springer-10.1007/s00421-006-0272-z The effect of acute exercise on endothelial function following a high-fat meal [Elektronische Daten] [Jaume Padilla, Ryan Harris, Alyce Fly, Lawrence Rink, Janet Wallace] The transient impairment of endothelial function following a high-fat meal is well established. Brachial artery flow-mediated dilation (FMD) decreases between 2 and 6h post ingestion. Whether this impairment can be reduced with acute aerobic exercise has not been investigated. The purpose of this study was to investigate if a single sustained aerobic exercise session can counteract the postprandial attenuation in brachial artery FMD associated with the ingestion of a high-fat meal. Eight apparently healthy adults (five men, three women), age 25.5±0.8years, performed three treatment conditions in a counter-balanced design: (1) low-fat meal alone (LFM), (2) high-fat meal alone (HFM), and (3) one session of aerobic exercise presented 2h after ingesting a high-fat meal (HFM-EX). The examination of brachial artery FMD was performed at baseline and 4h following the ingestion of the meal for each treatment condition. A 3×2 (treatment×time) repeated measures ANOVA exhibited a significant interaction (P=0.019). Preprandial FMDs were similar (P=0.863) among all three treatment conditions. The FMDs following the LFM (7.18±1.31%) and HFM-EX (8.72±0.94%) were significantly higher (P=0.001) than the FMD following the HFM (4.29±1.64%). FMD was significantly elevated above preprandial values following the HFM-EX (5.61±1.54 to 8.72±0.94%, P=0.005) but was unchanged following the LFM (6.17±0.94 to 7.18±1.31%, P=0.317) and the HFM (5.73±1.23 to 4.29±1.64%, P=0.160). These findings suggest that a single aerobic exercise session cannot only counteract the postprandial endothelial dysfunction induced by the ingestion of a high-fat meal, but also increase brachial artery FMD in apparently healthy adults. Springer-Verlag, 2006 Aerobic exercise nationallicence High-fat diet nationallicence Postprandial endothelial dysfunction nationallicence Flow-mediated dilation nationallicence Padilla Jaume Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, 47405, Bloomington, IN, USA aut Harris Ryan Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, 47405, Bloomington, IN, USA aut Fly Alyce Department of Applied Health Science, Nutrition Sciences Laboratory, Indiana University, 47405, Bloomington, IN, USA aut Rink Lawrence School of Medicine, Indiana University, 47405, Bloomington, IN, USA aut Wallace Janet Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, 47405, Bloomington, IN, USA aut European Journal of Applied Physiology Springer-Verlag 98/3(2006-10-01), 256-262 1439-6319 98:3<256 2006 98 421 https://doi.org/10.1007/s00421-006-0272-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0272-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Padilla Jaume Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, 47405, Bloomington, IN, USA aut NATIONALLICENCE 700 1- Harris Ryan Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, 47405, Bloomington, IN, USA aut NATIONALLICENCE 700 1- Fly Alyce Department of Applied Health Science, Nutrition Sciences Laboratory, Indiana University, 47405, Bloomington, IN, USA aut NATIONALLICENCE 700 1- Rink Lawrence School of Medicine, Indiana University, 47405, Bloomington, IN, USA aut NATIONALLICENCE 700 1- Wallace Janet Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, 47405, Bloomington, IN, USA aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/3(2006-10-01), 256-262 1439-6319 98:3<256 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer