caa a22 4500 467940215 CHVBK 20180406153010.0 cr unu---uuuuu 170328e20061101xx s 000 0 eng 10.1007/s00421-006-0285-7 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0285-7 Interleukin-6 response to isokinetic exercise in elite athletes: relationships to adrenocortical function and to mechanical and myoelectric fatigue [Elektronische Daten] [M. Minetto, A. Rainoldi, M. Gazzoni, G. Ganzit, L. Saba, P. Paccotti] Exercise stimulates the release of interleukin-6 (IL-6). Aims of the study were to: (a) analyse the IL-6 response to exercise in power (n=7) and endurance athletes (n=13); (b) determine the effects of the IL-6 production on mechanical and myoelectric fatigue; (c) evaluate the relationship between IL-6 and adrenocortical responses. EMG variables (conduction velocity, mean power frequency, average rectified value), ACTH, cortisol, DHEA, IL-6, myoglobin, and lactate were analysed before and after an isokinetic exercise. The exercise elicited significant mechanical and myoelectric fatigue as well as significant biochemical responses. Power athletes showed IL-6 and lactate responses higher than endurance athletes. The correlation analyses showed that the greater the mechanical fatigue, the greater the increases in lactate and IL-6. No correlations were found between IL-6 and EMG variables. No relationships were found between IL-6 and cortisol, after correction for ACTH levels. In conclusion, the muscular IL-6 production, as inferred by its circulating levels, had no detectable effects on the myoelectric manifestations of fatigue and the cortisol response to exercise was not related to the amount of circulating IL-6, but only to the activation of ACTH secretion. Springer-Verlag, 2006 Hypothalamic-pituitary-adrenal (HPA) axis nationallicence Interleukin-6 (IL-6) nationallicence Surface EMG nationallicence Myoelectric manifestations of fatigue nationallicence Isokinetic exercise nationallicence Minetto M. Divisione di Endocrinologia e Metabolismo, Dipartimento di Medicina Interna, Università di Torino, Torino, Italy aut Rainoldi A. Laboratorio di Ingegneria del Sistema Neuromuscolare (LISiN), Dipartimento di Elettronica, Politecnico di Torino, Torino, Italy aut Gazzoni M. Laboratorio di Ingegneria del Sistema Neuromuscolare (LISiN), Dipartimento di Elettronica, Politecnico di Torino, Torino, Italy aut Ganzit G. Istituto di Medicina dello Sport di Torino, Torino, Italy aut Saba L. Divisione di Medicina Interna, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Torino, Italy aut Paccotti P. Divisione di Medicina Interna, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Torino, Italy aut European Journal of Applied Physiology Springer-Verlag 98/4(2006-11-01), 373-382 1439-6319 98:4<373 2006 98 421 https://doi.org/10.1007/s00421-006-0285-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0285-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Minetto M. Divisione di Endocrinologia e Metabolismo, Dipartimento di Medicina Interna, Università di Torino, Torino, Italy aut NATIONALLICENCE 700 1- Rainoldi A. Laboratorio di Ingegneria del Sistema Neuromuscolare (LISiN), Dipartimento di Elettronica, Politecnico di Torino, Torino, Italy aut NATIONALLICENCE 700 1- Gazzoni M. Laboratorio di Ingegneria del Sistema Neuromuscolare (LISiN), Dipartimento di Elettronica, Politecnico di Torino, Torino, Italy aut NATIONALLICENCE 700 1- Ganzit G. Istituto di Medicina dello Sport di Torino, Torino, Italy aut NATIONALLICENCE 700 1- Saba L. Divisione di Medicina Interna, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Torino, Italy aut NATIONALLICENCE 700 1- Paccotti P. Divisione di Medicina Interna, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Torino, Italy aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/4(2006-11-01), 373-382 1439-6319 98:4<373 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer