caa a22 4500 467940320 CHVBK 20180406153010.0 cr unu---uuuuu 170328e20061101xx s 000 0 eng 10.1007/s00421-006-0290-x doi (NATIONALLICENCE)springer-10.1007/s00421-006-0290-x Maximal fat oxidation rates in endurance trained and untrained women [Elektronische Daten] [Anne Stisen, Ole Stougaard, Josef Langfort, Jørn Helge, Kent Sahlin, Klavs Madsen] The aim of the present study was to examine the differences in fat oxidation between endurance trained (ET) and untrained (UT) women. Eight ET and nine UT women performed a progressive cycle ergometer test until exhaustion. The rate of fat oxidation was similar at low work rates (≤90W) but was 80-200% higher in ET subjects at 120-180W. When related to relative exercise intensity, the fat oxidation was similar in the low-intensity domain (≤40% VO2max), but higher in the ET subjects both at moderate intensities (45-60% VO2max; +22% vs. UT) and at high intensities (65-80% VO2max; +35% vs. UT). There was no difference in the maximal fat oxidation rates between the trained and untrained women. The relative exercise intensity that elicited the highest rate of fat oxidation (Fatmax) was 56±3% and 53±2% VO2max in ET and UT women, respectively (NS). In biopsies from m. vastus lateralis, the activity of the enzymes citrate synthase, β-hydroxy acyl CoA dehydrogenase (HAD), and hormone sensitive lipase was higher in the ET subjects. The HAD activity correlated significantly with fat oxidation at moderate and high intensities. We conclude that the ET women had a higher fat oxidation at moderate- and high-exercise intensities both at same relative and at absolute intensity compared with the UT women. The HAD activity and fat oxidation rates were highly correlated indicating that training-induced adaptation in muscle fat oxidative capacity is an important factor for enhanced fat oxidation. Interestingly, maximal fat oxidation occurred at the same exercise intensity. Springer-Verlag, 2006 Endurance trained women nationallicence Progressive exercise test nationallicence Maximal fat oxidation nationallicence Hormone sensitive lipase nationallicence β-hydroxy acyl CoA dehydrogenase nationallicence Stisen Anne Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut Stougaard Ole Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut Langfort Josef Department of Pharmacology, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland aut Helge Jørn Copenhagen Muscle Research Centre, Department of Medical Physiology, University of Copenhagen, Copenhagen, Denmark aut Sahlin Kent Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut Madsen Klavs Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut European Journal of Applied Physiology Springer-Verlag 98/5(2006-11-01), 497-506 1439-6319 98:5<497 2006 98 421 https://doi.org/10.1007/s00421-006-0290-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0290-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stisen Anne Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut NATIONALLICENCE 700 1- Stougaard Ole Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut NATIONALLICENCE 700 1- Langfort Josef Department of Pharmacology, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland aut NATIONALLICENCE 700 1- Helge Jørn Copenhagen Muscle Research Centre, Department of Medical Physiology, University of Copenhagen, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Sahlin Kent Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut NATIONALLICENCE 700 1- Madsen Klavs Institute of Sports Sciences and Clinical Biomechanics, University of Southern Denmark, Odense University, Campusvej 55, 5230, Odense, Denmark aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/5(2006-11-01), 497-506 1439-6319 98:5<497 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer