caa a22 4500 46794038X CHVBK 20180406153010.0 cr unu---uuuuu 170328e20061101xx s 000 0 eng 10.1007/s00421-006-0303-9 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0303-9 Relationships between pulse wave velocity and heart rate variability in healthy men with a range of moderate-to-vigorous physical activity levels [Elektronische Daten] [G. Perkins, A. Owen, I. Swaine, J. Wiles] Pulse wave velocity (PWV) is associated with heart rate variability (HRV) in 24-39-year-old men. This study of 40-65-year-old men ranging in moderate-to-vigorous physical activity levels investigated whether (a) PWV is related to spectral HRV, (b) using normalised units for HRV influences that relationship, and (c) HRV predicts PWV when other factors, including age and blood pressure, are accounted for. Subjects were healthy men (N=115), mean (SD) age 50.8 (7.1) years. Carotid-femoral PWV was measured using Complior. HRV was derived from a 5min ECG for total, high-frequency, and low-frequency power (TP, HF, and LF, respectively), the LF/HF ratio, and normalised units for HF (HFnu) and LF (LFnu). Non-parametric data were natural log-transformed. PWV was 8.5 (1.4) ms−1. TP, HF, LF, LF/HF, HFnu and LFnu were 1908 (2195) ms2, 577 (1034) ms2, 457 (514) ms2, 1.5 (1.3), 46.8 (17.9), and 49.4 (19.4), respectively. PWV was inversely associated with TP (R 2=0.061, p=0.008), HF (R 2=0.095, p=0.001), LF (R 2=0.086, p=0.002) and HFnu (R 2=0.040, p=0.031), but was not associated with LF/HF (R 2=0.020, p=0.136) or LFnu (R 2=0.028 p=0.076). Only age and systolic blood pressure (adjusted R 2=0.306, p<0.001) predicted PWV in multivariate analysis. This study has shown that PWV was weakly associated with TP and HF. The use of normalised units only influenced the relationship between PWV and LF. Finally, relationships between PWV and HRV are mediated through age and systolic blood pressure in this population of men ranging in moderate-to-vigorous physical activity level. Springer-Verlag, 2006 Carotid-femoral pulse wave velocity nationallicence Arterial stiffness nationallicence Heart rate variability nationallicence Spectral power analysis nationallicence Autonomic nationallicence Perkins G. Sport Science, Tourism and Leisure, Canterbury Christ Church University, North Holmes Road, CT1 1QU, Canterbury, Kent, UK aut Owen A. Kent and Canterbury Hospital, Canterbury, Kent, UK aut Swaine I. Sport Science, Tourism and Leisure, Canterbury Christ Church University, North Holmes Road, CT1 1QU, Canterbury, Kent, UK aut Wiles J. Sport Science, Tourism and Leisure, Canterbury Christ Church University, North Holmes Road, CT1 1QU, Canterbury, Kent, UK aut European Journal of Applied Physiology Springer-Verlag 98/5(2006-11-01), 516-523 1439-6319 98:5<516 2006 98 421 https://doi.org/10.1007/s00421-006-0303-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0303-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Perkins G. Sport Science, Tourism and Leisure, Canterbury Christ Church University, North Holmes Road, CT1 1QU, Canterbury, Kent, UK aut NATIONALLICENCE 700 1- Owen A. Kent and Canterbury Hospital, Canterbury, Kent, UK aut NATIONALLICENCE 700 1- Swaine I. Sport Science, Tourism and Leisure, Canterbury Christ Church University, North Holmes Road, CT1 1QU, Canterbury, Kent, UK aut NATIONALLICENCE 700 1- Wiles J. Sport Science, Tourism and Leisure, Canterbury Christ Church University, North Holmes Road, CT1 1QU, Canterbury, Kent, UK aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/5(2006-11-01), 516-523 1439-6319 98:5<516 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer