caa a22 4500 467940746 CHVBK 20180406153011.0 cr unu---uuuuu 170328e20060401xx s 000 0 eng 10.1007/s00421-005-0119-z doi (NATIONALLICENCE)springer-10.1007/s00421-005-0119-z Effects of resistance exercise session after oral ingestion of melatonin on physiological and performance responses of adult men [Elektronische Daten] [Antti Mero, Mika Vähälummukka, Juha Hulmi, Petteri Kallio, Atte von Wright] This study investigated the effects of a heavy resistance exercise session (RES) with the oral daytime ingestion of melatonin on the physiological responses and acute performance. In a randomized and double-blind controlled study 10 healthy male subjects undertook an 80min intensive hypertrophic RES for major muscles of the lower and upper extremities. The subjects were studied on two occasions receiving either melatonin (6mg) or placebo (6mg) in random order 60min before each RES. Blood samples were taken from an antecubital vein both in fasting conditions in the morning and before RES (pre 60min, pre 0min), during RES (middle) and after RES (post 0min, post 15min, post 30min, post 60min). Maximal jumping ability and maximal strength in bench press and squat were measured before and immediately after RES in which there were no differences between the melatonin and placebo groups. The serum melatonin concentration increased significantly (P<0.05-0.001) in the melatonin group following oral ingestion of melatonin and was elevated at every time point after that. The concentration reached a peak value of 1171.3±235.2pg/ml in 60min at pre 0. Serum melatonin increased slightly but significantly (P<0.05) also in the placebo group just before RES, in the middle of RES and after RES (post 0, post 15). There were large differences (P<0.01-0.001) in the serum melatonin concentration between the groups at all time points. There were no differences in the growth hormone (GH), testosterone and cortisol peak concentrations at any time points between the groups but the area under the curve of GH during RES (P<0.01) and during the 60min after RES (P<0.05) was lower in the melatonin condition. In conclusion, the present findings give evidence that oral ingestion of melatonin (6mg) during daytime with heavy resistance exercise may slightly decrease GH concentrations. On the other hand, it seems that melatonin administration during daytime does not have any acute (1-2h) effects either on the maximal jumping ability or on the maximal strength. Springer-Verlag, 2006 Melatonin nationallicence Serum hormones nationallicence Exercise intensity nationallicence Performance nationallicence Mero Antti Department of Biology of Physical Activity, University of Jyväskylä, 40014, Jyvaskyla, Finland aut Vähälummukka Mika Department of Biology of Physical Activity, University of Jyväskylä, 40014, Jyvaskyla, Finland aut Hulmi Juha Department of Biology of Physical Activity, University of Jyväskylä, 40014, Jyvaskyla, Finland aut Kallio Petteri Food and Health Research Centre, University of Kuopio, 70200, Kuopio, Finland aut von Wright Atte Institute of Applied Biotechnology, University of Kuopio, 70200, Kuopio, Finland aut European Journal of Applied Physiology Springer-Verlag 96/6(2006-04-01), 729-739 1439-6319 96:6<729 2006 96 421 https://doi.org/10.1007/s00421-005-0119-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-005-0119-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mero Antti Department of Biology of Physical Activity, University of Jyväskylä, 40014, Jyvaskyla, Finland aut NATIONALLICENCE 700 1- Vähälummukka Mika Department of Biology of Physical Activity, University of Jyväskylä, 40014, Jyvaskyla, Finland aut NATIONALLICENCE 700 1- Hulmi Juha Department of Biology of Physical Activity, University of Jyväskylä, 40014, Jyvaskyla, Finland aut NATIONALLICENCE 700 1- Kallio Petteri Food and Health Research Centre, University of Kuopio, 70200, Kuopio, Finland aut NATIONALLICENCE 700 1- von Wright Atte Institute of Applied Biotechnology, University of Kuopio, 70200, Kuopio, Finland aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 96/6(2006-04-01), 729-739 1439-6319 96:6<729 2006 96 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer