caa a22 4500 467940967 CHVBK 20180406153012.0 cr unu---uuuuu 170328e20060201xx s 000 0 eng 10.1007/s00421-005-0058-8 doi (NATIONALLICENCE)springer-10.1007/s00421-005-0058-8 Metabolic fate of a large amount of 13C-glycerol ingested during prolonged exercise [Elektronische Daten] [D. Massicotte, A. Scotto, F. Péronnet, H. M'Kaouar, M. Milot, C. Lavoie] We have shown that the oxidation rate of exogenous glycerol and glucose during prolonged exercise were similar when ingested in small amounts (0.36g/kg) (J Appl Physiol 90:1685,2001). The oxidation rate of exogenous carbohydrate increases with the amount ingested. We, thus, hypothesized that the oxidation rate of exogenous glycerol would also be larger when ingested in large amount. The study was conducted on six male subjects exercising for 120min at 64 (2)%VO2max while ingesting 1g/kg of 13C-glycerol. Substrate oxidation was measured using indirect respiratory calorimetry corrected for protein oxidation, and from V 13CO2at the mouth. The 13C enrichment of plasma glucose was also measured in order to follow the possible conversion of 13C-glycerol into glucose. In spite of the large amount of glycerol ingested and absorbed (plasma glycerol concentration = 8.0 (0.3)mmol/l at min 100), exogenous glycerol oxidation over the last 80min of exercise [8.8 (1.6)g providing 4.1 (0.7)% of the energy yield] was similar to that observed when 0.36g/kg was ingested. The comparison between the 13C enrichment of plasma glucose and the oxidation rate of 13C-glycerol showed that a portion of exogenous glycerol was converted into glucose before being oxidized, but also suggested that another portion could have been directly oxidized in peripheral tissues. Springer-Verlag, 2005 Exogenous glycerol nationallicence Indirect calorimetry nationallicence Stable isotopes nationallicence Gluconeogenesis nationallicence Massicotte D. Département de kinanthropologie, Université du Québec à Montréal, CP 8888, H3C 3P8, Centre Ville, Montréal, QC, Canada aut Scotto A. Département de kinésiologie, Université de Montréal, CP 6128, H3C 3J7, Centre Ville, Montréal, QC, Canada aut Péronnet F. Département de kinésiologie, Université de Montréal, CP 6128, H3C 3J7, Centre Ville, Montréal, QC, Canada aut M'Kaouar H. Département de kinésiologie, Université de Montréal, CP 6128, H3C 3J7, Centre Ville, Montréal, QC, Canada aut Milot M. Département des sciences de l'activité physique, Université du Québec à Trois Rivières, CP 500, G9A 5H7, Trois Rivières, QC, Canada aut Lavoie C. Département des sciences de l'activité physique, Université du Québec à Trois Rivières, CP 500, G9A 5H7, Trois Rivières, QC, Canada aut European Journal of Applied Physiology Springer-Verlag 96/3(2006-02-01), 322-329 1439-6319 96:3<322 2006 96 421 https://doi.org/10.1007/s00421-005-0058-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-005-0058-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Massicotte D. Département de kinanthropologie, Université du Québec à Montréal, CP 8888, H3C 3P8, Centre Ville, Montréal, QC, Canada aut NATIONALLICENCE 700 1- Scotto A. Département de kinésiologie, Université de Montréal, CP 6128, H3C 3J7, Centre Ville, Montréal, QC, Canada aut NATIONALLICENCE 700 1- Péronnet F. Département de kinésiologie, Université de Montréal, CP 6128, H3C 3J7, Centre Ville, Montréal, QC, Canada aut NATIONALLICENCE 700 1- M'Kaouar H. Département de kinésiologie, Université de Montréal, CP 6128, H3C 3J7, Centre Ville, Montréal, QC, Canada aut NATIONALLICENCE 700 1- Milot M. Département des sciences de l'activité physique, Université du Québec à Trois Rivières, CP 500, G9A 5H7, Trois Rivières, QC, Canada aut NATIONALLICENCE 700 1- Lavoie C. Département des sciences de l'activité physique, Université du Québec à Trois Rivières, CP 500, G9A 5H7, Trois Rivières, QC, Canada aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 96/3(2006-02-01), 322-329 1439-6319 96:3<322 2006 96 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer