caa a22 4500 467941033 CHVBK 20180406153012.0 cr unu---uuuuu 170328e20060301xx s 000 0 eng 10.1007/s00421-005-0083-7 doi (NATIONALLICENCE)springer-10.1007/s00421-005-0083-7 Interactions between exposure to hypoxia and the training-induced autonomic adaptations in a "live high-train low” session [Elektronische Daten] [Jérémy Cornolo, Jean-Pierre Fouillot, Laurent Schmitt, Camillo Povea, Paul Robach, Jean-Paul Richalet] The autonomic and cardiovascular adaptations to hypoxia are opposite to those resulting from aerobic training. We investigated (1) whether exposure to hypoxia in a live high-train low (LHTL) session limits the autonomic and cardiovascular adaptations to training, and (2) whether such interactions remain 15days after the end of the LHTL. Eighteen national swimmers trained for 13days at 1,200m, living (16hday−1) either at 1,200m (live low-train low, LLTL) or at a simulated height of 2,500-3,000m (LHTL). Subjects were investigated at 1,200m before and at the end of the training session, and after the following 15days of sea-level training. Cardiovascular parameters and the autonomic control assessed by spectral analysis of R-R and diastolic blood pressure (DBP) variability were obtained in the resting supine position and in response to an orthostatic test. At the end of the 13-day training, resting heart rate (HR) and sympathetic modulation on heart decreased in LLTL (−10.1% and −25.4%, P<0.01, respectively) but not in LHTL (−5.8, −15.5%, respectively). Total peripheral resistance (TPR) and DBP became higher in LHTL than in LLTL (P<0.05). Stroke index decreased in both groups during the tilt test, counteracted by an increase in HR and sympathetic modulation to the heart and vasculature, and a decrease in vagal modulation to the heart. After the following 15-day sea-level training, differences in TPR and DBP between groups disappeared. During an LHTL session, adaptations to hypoxia interacted with the autonomic and cardiovascular adaptations to training. However, these interactions did not limit the adaptations to the following sea-level training. Springer-Verlag, 2005 Heart rate variability nationallicence Live high-train low nationallicence Hypoxia nationallicence Training nationallicence Orthostatic test nationallicence Cornolo Jérémy Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut Fouillot Jean-Pierre Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut Schmitt Laurent Centre National de Ski Nordique, ID Jacobeys, 39200, Prémanon, France aut Povea Camillo Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut Robach Paul Ecole Nationale de Ski et d'Alpinisme, 74401, Chamonix, France aut Richalet Jean-Paul Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut European Journal of Applied Physiology Springer-Verlag 96/4(2006-03-01), 389-396 1439-6319 96:4<389 2006 96 421 https://doi.org/10.1007/s00421-005-0083-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-005-0083-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cornolo Jérémy Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut NATIONALLICENCE 700 1- Fouillot Jean-Pierre Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut NATIONALLICENCE 700 1- Schmitt Laurent Centre National de Ski Nordique, ID Jacobeys, 39200, Prémanon, France aut NATIONALLICENCE 700 1- Povea Camillo Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut NATIONALLICENCE 700 1- Robach Paul Ecole Nationale de Ski et d'Alpinisme, 74401, Chamonix, France aut NATIONALLICENCE 700 1- Richalet Jean-Paul Laboratoire, Réponses cellulaires et fonctionnelles à l'hypoxie, Université Paris 13, EA2363, ARPE, 93017, Bobigny, France aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 96/4(2006-03-01), 389-396 1439-6319 96:4<389 2006 96 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer