caa a22 4500 467941092 CHVBK 20180406153012.0 cr unu---uuuuu 170328e20060301xx s 000 0 eng 10.1007/s00421-005-0084-6 doi (NATIONALLICENCE)springer-10.1007/s00421-005-0084-6 Effect of concentric or eccentric weight training on the expression of heat shock proteins in m. biceps brachii of very well trained males [Elektronische Daten] [Terje Gjøvaag, Harald Vikne, Hans Dahl] Increased HSP expression in response to acute exercise is well documented in animal studies, and there is growing evidence that similar responses occur in man. In general, many human exercise studies have investigated the HSP response to low force continuous activity, while the knowledge about the HSP response to high force intermittent type of activity, like weight training, is so far sparse. In addition, most studies have used untrained subjects, and a common observation is that acute low force continuous activity in untrained individuals increases the HSP expression in these individuals. The main scope of this study was to investigate the HSP response in very well trained males subjected to longitudinal high intensity exercise, and if this response was dependent on exercise modality [i.e. eccentric (ECC) or concentric (CON) contractions]. Very well trained males performed progressive strength training consisting of either high force ECC or high force CON elbow flexions 2-3 times a week for 12weeks. Compared with pre-exercise levels, HSP72 expression decreased by 46.1% (P<0.05) after CON contractions. GRP75 expression was unchanged after ECC or CON contractions, while ubiquitin expression decreased by 19.9% (P<0.02) after ECC contractions. These findings imply that chronic, intensive exercise may attenuate the HSP response in well-trained males. Springer-Verlag, 2005 HSP72 nationallicence GRP75 nationallicence Ubiquitin nationallicence Exercise nationallicence Athletes nationallicence Gjøvaag Terje Oslo University College, St Olavs Plass, PO Box 4, 0130, Oslo, Norway aut Vikne Harald Norwegian School of Sport Sciences, Ullevål Stadion, PO Box 4014, 0806, Oslo, Norway aut Dahl Hans Norwegian School of Sport Sciences, Ullevål Stadion, PO Box 4014, 0806, Oslo, Norway aut European Journal of Applied Physiology Springer-Verlag 96/4(2006-03-01), 355-362 1439-6319 96:4<355 2006 96 421 https://doi.org/10.1007/s00421-005-0084-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-005-0084-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gjøvaag Terje Oslo University College, St Olavs Plass, PO Box 4, 0130, Oslo, Norway aut NATIONALLICENCE 700 1- Vikne Harald Norwegian School of Sport Sciences, Ullevål Stadion, PO Box 4014, 0806, Oslo, Norway aut NATIONALLICENCE 700 1- Dahl Hans Norwegian School of Sport Sciences, Ullevål Stadion, PO Box 4014, 0806, Oslo, Norway aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 96/4(2006-03-01), 355-362 1439-6319 96:4<355 2006 96 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer