caa a22 4500 467941971 CHVBK 20180406153015.0 cr unu---uuuuu 170328e20060701xx s 000 0 eng 10.1007/s00421-006-0203-z doi (NATIONALLICENCE)springer-10.1007/s00421-006-0203-z A single open sea air dive increases pulmonary artery pressure and reduces right ventricular function in professional divers [Elektronische Daten] [Željko Dujić, Ante Obad, Ivan Palada, Zoran Valic, Alf Brubakk] After decompression from dives, bubbles are frequently observed in the right ventricular outflow tract and may lead to vascular damage, pulmonary arterial hypertension and right ventricular overload. No data exist on the effect of open sea diving on the pulmonary artery pressure (PAP). Eight professional divers performed an open sea air dive to 30msw. Before and postdive a Doppler echocardiographic study was undertaken. Systolic pulmonary artery pressure (SPAP) was estimated from measurement of peak flow velocity of the tricuspid regurgitant jet; the ratio between pulmonary artery acceleration times (AccT) and right ventricular ejection time (RVET) was used as an estimate of the mean PAP. No evidence of either patent foramen ovale or intra-pulmonary shunt was found in any subject postdive after performing a Valsalva maneuver. SPAP increased from 25±3 to 33±2mmHg and AccT/RVET ratio decreased from 0.44±0.04 to 0.3±0.02 20min after the dive, respectively. Pulmonary vascular resistance increased from 1.2±0.1 to 1.4±0.1 Woods Units. Postdive right ventricle end-diastolic and end-systolic volumes were increased for about 19% (P=0.001) and 33% (P=0.001) and right ejection fraction decreased about for 6% (P=0.001). Cardiac output decreased from 4.8±0.9 (lmin−1) to 4.0±0.6 at 40min postdive due to decreases in heart rate and stroke volume. This study shows that a single open sea dive may be associated with right heart overload due to increased pressure in the pulmonary artery. Springer-Verlag, 2006 Diving nationallicence Pulmonary artery pressure nationallicence Professional nationallicence Cardiac output nationallicence Gas bubbles nationallicence Dujić Željko Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut Obad Ante Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut Palada Ivan Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut Valic Zoran Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut Brubakk Alf Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway aut European Journal of Applied Physiology Springer-Verlag 97/4(2006-07-01), 478-485 1439-6319 97:4<478 2006 97 421 https://doi.org/10.1007/s00421-006-0203-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0203-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dujić Željko Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut NATIONALLICENCE 700 1- Obad Ante Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut NATIONALLICENCE 700 1- Palada Ivan Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut NATIONALLICENCE 700 1- Valic Zoran Department of Physiology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia aut NATIONALLICENCE 700 1- Brubakk Alf Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 97/4(2006-07-01), 478-485 1439-6319 97:4<478 2006 97 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer