caa a22 4500 467942137 CHVBK 20180406153016.0 cr unu---uuuuu 170328e20060701xx s 000 0 eng 10.1007/s00421-006-0223-8 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0223-8 Protein supplementation before and after resistance training in older men [Elektronische Daten] [Darren Candow, Philip Chilibeck, Marina Facci, Saman Abeysekara, Gordon Zello] We determined the effects of protein supplementation immediately before (PRO-B) and after (PRO-A) resistance training (RT; 12 weeks) in older men (59-76 years), and whether this reduces deficits in muscle mass and strength compared to younger men (18-40 years). Older men were randomized to PRO-B (0.3g/kg protein before RT+placebo after RT, n=9), PRO-A (placebo before+protein after RT, n=10), or PLA (placebo before and after RT, n=10). Lean tissue mass, muscle thickness of the elbow, knee, and ankle flexors and extensors, and leg and bench press strength were measured before and after RT and compared to databases of younger subjects (n=22-60). Myofibrillar protein degradation (3-methylhistidine) and bone resorption (cross-linked N-telopeptides) were also measured before and after RT. Lean tissue mass, muscle thickness (except ankle dorsi flexors), and strength increased with training (P<0.05), with little difference between groups. There were no changes in 3-methylhistidine or cross-linked N-telopeptides. Before RT, all measures were lower in the older compared to younger groups (P<0.05), except for elbow extensor muscle thickness. Following training, muscle thickness of the elbow flexors and ankle dorsi flexors and leg press strength were no longer different than the young, and elbow extensor muscle thickness was greater in the old men (P<0.05). Supplementation with protein before or after training has no effect on muscle mass and strength in older men. RT was sufficient to overcome deficits in muscle size of the elbow flexors and ankle dorsi flexors and leg press strength in older compared to younger men. Springer-Verlag, 2006 Age nationallicence Muscle nationallicence Strength nationallicence Catabolism nationallicence Bone nationallicence Candow Darren School of Human Kinetics, Laurentian University, Sudbury, ON, Canada aut Chilibeck Philip College of Kinesiology, University of Saskatchewan, 87 Campus Drive, S7N 5B2, Saskatoon, SK, Canada aut Facci Marina Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada aut Abeysekara Saman College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada aut Zello Gordon College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada aut European Journal of Applied Physiology Springer-Verlag 97/5(2006-07-01), 548-556 1439-6319 97:5<548 2006 97 421 https://doi.org/10.1007/s00421-006-0223-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0223-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Candow Darren School of Human Kinetics, Laurentian University, Sudbury, ON, Canada aut NATIONALLICENCE 700 1- Chilibeck Philip College of Kinesiology, University of Saskatchewan, 87 Campus Drive, S7N 5B2, Saskatoon, SK, Canada aut NATIONALLICENCE 700 1- Facci Marina Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada aut NATIONALLICENCE 700 1- Abeysekara Saman College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada aut NATIONALLICENCE 700 1- Zello Gordon College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 97/5(2006-07-01), 548-556 1439-6319 97:5<548 2006 97 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer