caa a22 4500 467942145 CHVBK 20180406153016.0 cr unu---uuuuu 170328e20060701xx s 000 0 eng 10.1007/s00421-006-0208-7 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0208-7 Distance of walking in childhood and femoral bone density in perimenopausal women [Elektronische Daten] [Toni Rikkonen, Marjo Tuppurainen, Heikki Kröger, Jukka Jurvelin, Risto Honkanen] Kuopio osteoporosis risk factor and prevention (OSTPRE) study is a population-based study from Eastern Finland. At baseline in 1989-91, bone densitometry of lumbar spine and femoral neck as assessed by DXA was carried out on women aged 48-58 (n=3,222). In 1993, menarcheal age and health habits during adolescence were inquired from a postal inquiry. In 1996, a random sample of 254 women who had been premenopausal at baseline was interviewed over phone. They were asked how many kilometers per day they had walked to school and back, in each grade of primary school. The study sample (N=185) was formed by excluding women with menarcheal age of >14 or <11years. Women with any reported HRT history were also excluded. The mean age of the study sample was 50.7 (1.63) years, weight 70.8 (13.1) kg, height 161.5 (5.0) cm, and mean walking distance to and fro from the school at ages from 9 to 11years was 2.7 (1.7) km. In regression analysis, the walking distance was associated with femoral BMD (r=0.18, P=0.015). After adjusting for baseline age, weight and height, this association persisted (P=0.025). When walking distance was categorized as I=0-0.549km, II=0.55-1.99km, III=2.0-4.99 and IV=5.0km and more, the respective means for femoral BMDs were 0.92, 0.97, 0.98 and 1.01g/cm2. Statistical significance persisted after adjusting for height, weight, age, grip strength, calcium intake, smoking, place of residence, use of contraceptive pills, physical load of work and baseline physical activity (P=0.032). A 10year follow-up revealed no changes in bone loss rate between the groups and femoral BMD benefits persisted (repeated measures analysis=NS). Walking distance was not associated with spinal bone density. Even though walking is a low impact activity, walking before menarche may have a moderate but long-lasting positive effect on femoral peak bone density. Lack of walking and similar low impact physical activities during peak growth years may have a negative effect on peak bone mass formation. Springer-Verlag, 2006 Rikkonen Toni Research Institute of Public Health, University of Kuopio, 1627, 70211, Kuopio, Finland aut Tuppurainen Marjo Bone and Cartilage Research Unit, University of Kuopio, Kuopio, Finland aut Kröger Heikki Department of Surgery, Kuopio University Hospital, Kuopio, Finland aut Jurvelin Jukka Department of Physics, University of Kuopio, Kuopio, Finland aut Honkanen Risto Research Institute of Public Health, University of Kuopio, 1627, 70211, Kuopio, Finland aut European Journal of Applied Physiology Springer-Verlag 97/5(2006-07-01), 509-515 1439-6319 97:5<509 2006 97 421 https://doi.org/10.1007/s00421-006-0208-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0208-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rikkonen Toni Research Institute of Public Health, University of Kuopio, 1627, 70211, Kuopio, Finland aut NATIONALLICENCE 700 1- Tuppurainen Marjo Bone and Cartilage Research Unit, University of Kuopio, Kuopio, Finland aut NATIONALLICENCE 700 1- Kröger Heikki Department of Surgery, Kuopio University Hospital, Kuopio, Finland aut NATIONALLICENCE 700 1- Jurvelin Jukka Department of Physics, University of Kuopio, Kuopio, Finland aut NATIONALLICENCE 700 1- Honkanen Risto Research Institute of Public Health, University of Kuopio, 1627, 70211, Kuopio, Finland aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 97/5(2006-07-01), 509-515 1439-6319 97:5<509 2006 97 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer