caa a22 4500 46794220X CHVBK 20180406153016.0 cr unu---uuuuu 170328e20060701xx s 000 0 eng 10.1007/s00421-006-0216-7 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0216-7 Effects of 30 versus 60min of low-load work on intramuscular lactate, pyruvate, glutamate, prostaglandin E2 and oxygenation in the trapezius muscle of healthy females [Elektronische Daten] [G. Flodgren, F. Hellström, M. Fahlström, A. Crenshaw] The aim of this study was to investigate the effects of duration of low-load repetitive work on intramuscular lactate, pyruvate, glutamate and prostaglandin E2 (PGE2), and oxygen saturation in the trapezius muscle. Twenty healthy females were studied during baseline rest, during low-load repetitive work for either 30 (REP 30) or 60min (REP 60) and 60min recovery. Intramuscular microdialysate (IMMD) samples were obtained, and local muscle tissue oxygenation (%StO2) assessed with near-infrared spectroscopy (NIRS). Subjects rated their perceived exertion (Borg CR-10 scale) and capillary blood was sampled for lactate analysis. The results showed a significant increase in IMMD lactate in response to both REP 30 and REP 60 (P<0.05 and P<0.01, respectively) and glutamate (P<0.0001), but no progressive increase with increasing work duration. Both IMMD pyruvate and lactate tended to be significantly increased during the recovery period. No corresponding increase in blood lactate was found. Local muscle %StO2 did not change significantly in response to work and was not correlated to the IMMD lactate concentration. The ratings of perceived exertion increased in response to work, and remained increased after recovery for REP 60. In conclusion, the results of this study show significantly increased IMMD lactate and, glutamate concentrations in the trapezius muscle of healthy females in response to low-load work, but no progressive increase with increased work duration. Further, they do not indicate that the increased IMMD lactate concentration was caused by a locally decreased or insufficient muscle tissue oxygenation. Springer-Verlag, 2006 Microdialysis nationallicence Near-infrared spectroscopy nationallicence Perceived muscle fatigue nationallicence Flodgren G. Centre for Musculoskeletal Research, University of Gävle, P.O. Box 7629, 907 12, Umeå, Sweden aut Hellström F. Centre for Musculoskeletal Research, University of Gävle, P.O. Box 7629, 907 12, Umeå, Sweden aut Fahlström M. Department of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, 901 87, Umeå, Sweden aut Crenshaw A. Centre for Musculoskeletal Research, University of Gävle, P.O. Box 7629, 907 12, Umeå, Sweden aut European Journal of Applied Physiology Springer-Verlag 97/5(2006-07-01), 557-565 1439-6319 97:5<557 2006 97 421 https://doi.org/10.1007/s00421-006-0216-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0216-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Flodgren G. Centre for Musculoskeletal Research, University of Gävle, P.O. Box 7629, 907 12, Umeå, Sweden aut NATIONALLICENCE 700 1- Hellström F. Centre for Musculoskeletal Research, University of Gävle, P.O. Box 7629, 907 12, Umeå, Sweden aut NATIONALLICENCE 700 1- Fahlström M. Department of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, 901 87, Umeå, Sweden aut NATIONALLICENCE 700 1- Crenshaw A. Centre for Musculoskeletal Research, University of Gävle, P.O. Box 7629, 907 12, Umeå, Sweden aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 97/5(2006-07-01), 557-565 1439-6319 97:5<557 2006 97 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer