caa a22 4500 467942331 CHVBK 20180406153016.0 cr unu---uuuuu 170328e20060501xx s 000 0 eng 10.1007/s00421-005-0127-z doi (NATIONALLICENCE)springer-10.1007/s00421-005-0127-z Independent and combined effects of liquid carbohydrate/essential amino acid ingestion on hormonal and muscular adaptations following resistance training in untrained men [Elektronische Daten] [Stephen Bird, Kyle Tarpenning, Frank Marino] This investigation examined chronic alteration of the acute hormonal response associated with liquid carbohydrate (CHO) and/or essential amino acid (EAA) ingestion on hormonal and muscular adaptations following resistance training. Thirty-two untrained young men performed 12weeks of resistance training twice a week, consuming ~675ml of either, a 6% CHO solution, 6g EAA mixture, combined CHO+EAA supplement or placebo (PLA). Blood samples were obtained pre- and post-exercise (week 0, 4, 8, and 12), for determination of glucose, insulin, and cortisol. 3-Methylhistidine excretion and muscle fibre cross-sectional area (fCSA) were determined pre- and post-training. Post-exercise cortisol increased (P<0.05) during each training phase for PLA. No change was displayed by EAA; CHO and CHO+EAA demonstrated post-exercise decreases (P<0.05). All groups displayed reduced pre-exercise cortisol at week 12 compared to week 0 (P<0.05). Post-exercise insulin concentrations showed no change for PLA; increases were observed for the treatment groups (P<0.05), which remained greater for CHO and CHO+EAA (P<0.001) than PLA. EAA and CHO ingestion attenuated 3-methylhistidine excretion 48h following the exercise bout. CHO+EAA resulted in a 26% decrease (P<0.01), while PLA displayed a 52% increase (P<0.01). fCSA increased across groups for type I, IIa, and IIb fibres (P<0.05), with CHO+EAA displaying the greatest gains in fCSA relative to PLA (P<0.05). These data indicate that CHO+EAA ingestion enhances muscle anabolism following resistance training to a greater extent than either CHO or EAA consumed independently. The synergistic effect of CHO+EAA ingestion maximises the anabolic response presumably by attenuating the post-exercise rise in protein degradation. Springer-Verlag, 2006 Resistance training nationallicence Supplementation nationallicence Cortisol nationallicence Insulin nationallicence Hypertrophy nationallicence Bird Stephen School of Human Movement Studies, Charles Sturt University, Allen House 2.13, Bathurst, NSW, Australia aut Tarpenning Kyle School of Human Movement Studies, Charles Sturt University, Allen House 2.13, Bathurst, NSW, Australia aut Marino Frank School of Human Movement Studies, Charles Sturt University, Allen House 2.13, Bathurst, NSW, Australia aut European Journal of Applied Physiology Springer-Verlag 97/2(2006-05-01), 225-238 1439-6319 97:2<225 2006 97 421 https://doi.org/10.1007/s00421-005-0127-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-005-0127-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bird Stephen School of Human Movement Studies, Charles Sturt University, Allen House 2.13, Bathurst, NSW, Australia aut NATIONALLICENCE 700 1- Tarpenning Kyle School of Human Movement Studies, Charles Sturt University, Allen House 2.13, Bathurst, NSW, Australia aut NATIONALLICENCE 700 1- Marino Frank School of Human Movement Studies, Charles Sturt University, Allen House 2.13, Bathurst, NSW, Australia aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 97/2(2006-05-01), 225-238 1439-6319 97:2<225 2006 97 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 467942331 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer