caa a22 4500 467942390 CHVBK 20180406153017.0 cr unu---uuuuu 170328e20060501xx s 000 0 eng 10.1007/s00421-006-0155-3 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0155-3 Effects of short supramaximal exercise on hemorheology in sickle cell trait carriers [Elektronische Daten] [Philippe Connes, Fagnété Sara, Marie-Dominique Hardy-Dessources, Laurent Marlin, Frantz Etienne, Laurent Larifla, Christian Saint-Martin, Olivier Hue] This study compared the hemorheological profile at rest and in response to a short supramaximal exercise test between sickle cell trait (SCT) carriers and a control group. Eight SCT carriers and eight control subjects performed a ramp exercise test on a cycle ergometer conducted to maximal oxygen uptake $$(\dot{V}{\text{O}}_{2{\text{max}}}).$$ One week later, they performed a supramaximal exercise test consisting of pedaling for 1min at 110% $$\dot{V}{\text{O}}_{2{\text{max}}}.$$ Blood viscosity (ηb), plasma viscosity (ηp), hematocrit (Hct) and red blood cell (RBC) rigidity were assessed at rest, at the end of exercise and at the 15th, 30th and 60thmin of recovery. Exercise increased ηb, ηp and Hct above resting values in both groups and these parameters remained higher until the 15th or 30thmin of recovery as compared to resting values. RBC rigidity was unchanged from baseline values in both groups during exercise and recovery. No difference was observed between the two groups for ηp and Hct but ηb and RBC rigidity were higher in the SCT carriers at every time point compared with the control group. The higher RBC rigidity and ηb found in SCT carriers at rest and in response to a brief supramaximal exercise might constitute a risk factor for microcirculatory complications. Indeed, a short supramaximal exercise test may not be completely inoffensive for SCT carriers. Springer-Verlag, 2006 Exercise nationallicence Red blood cell rigidity nationallicence Blood viscosity nationallicence Hemoglobinopathy nationallicence Connes Philippe Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut Sara Fagnété Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut Hardy-Dessources Marie-Dominique UMR S 458 Inserm, Centre Hospitalier Universitaire, Université des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe aut Marlin Laurent Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut Etienne Frantz Service de Cardiologie, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe aut Larifla Laurent Service de Cardiologie, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe aut Saint-Martin Christian Centre Caribéen de la Drépanocytose "Guy Mérault”, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe aut Hue Olivier Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut European Journal of Applied Physiology Springer-Verlag 97/2(2006-05-01), 143-150 1439-6319 97:2<143 2006 97 421 https://doi.org/10.1007/s00421-006-0155-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0155-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Connes Philippe Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut NATIONALLICENCE 700 1- Sara Fagnété Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut NATIONALLICENCE 700 1- Hardy-Dessources Marie-Dominique UMR S 458 Inserm, Centre Hospitalier Universitaire, Université des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe aut NATIONALLICENCE 700 1- Marlin Laurent Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut NATIONALLICENCE 700 1- Etienne Frantz Service de Cardiologie, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe aut NATIONALLICENCE 700 1- Larifla Laurent Service de Cardiologie, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe aut NATIONALLICENCE 700 1- Saint-Martin Christian Centre Caribéen de la Drépanocytose "Guy Mérault”, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe aut NATIONALLICENCE 700 1- Hue Olivier Laboratoire ACTES (EA 3596), Université des Antilles et de la Guyane, Campus de Fouillole, 97159, Pointe-à-Pitre, Guadeloupe (French West Indies) aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 97/2(2006-05-01), 143-150 1439-6319 97:2<143 2006 97 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer