caa a22 4500 467944474 CHVBK 20180405193735.0 cr unu---uuuuu 170328e20050301xx s 000 0 eng 10.1007/PL00022044 doi (NATIONALLICENCE)springer-10.1007/PL00022044 (NATIONALLICENCE)springer-10.1007/s11055-005-0063-8 The effects of 6-Hydroxydopamine on the electrical characteristics of snail neurons in long-term sensitization [Elektronische Daten] [V. Andrianov, R. Tagirova, Kh. Gainutdinov, T. Gainutdinova, A. Golubev, L. Muranova] The effects of the neurotoxin 6-hydroxydopamine on the formation of long-term sensitization and changes in the membrane characteristics of identified neurons were studied. Injections of the neurotoxin 6-hydroxydopamine blocked the acquisition of long-term sensitization; when neurotoxin injections were given after the formation of long-term sensitization, they had no subsequent effect on conduction parameters. At the cellular level, recording of the electrical characteristics of common snail defensive behavior command neurons (LPa3, RPa3, LPa2, and RPa2) showed that the effects of 6-hydroxydopamine consisted of a small depolarization shift in the membrane potential and a change in the action potential generation threshold. Formation of long-term sensitization after injections of 6-hydroxydopamine did not lead to further decreases in the membrane and threshold potentials of command neurons as compared with snails only given injections of 6-hydroxydopamine. The changes in electrical measures of command neurons induced by administration of the neurotoxin 6-hydroxydopamine lasted at least two weeks. Springer Science+Business Media, Inc., 2005 dopamine nationallicence plasticity nationallicence long-term sensitization nationallicence membrane potential nationallicence threshold potential nationallicence 6-hydroxydopamine nationallicence Andrianov V. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut Tagirova R. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut Gainutdinov Kh Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut Gainutdinova T. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut Golubev A. Department of Invertebrate Zoology, Kazan' State University, 18 Kremlevskaya Street, 420008, Kazan', Russia aut Muranova L. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut Neuroscience and Behavioral Physiology Kluwer Academic Publishers-Consultants Bureau 35/3(2005-03-01), 305-311 0097-0549 35:3<305 2005 35 11055 https://doi.org/10.1007/PL00022044 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00022044 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Andrianov V. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut NATIONALLICENCE 700 1- Tagirova R. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut NATIONALLICENCE 700 1- Gainutdinov Kh Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut NATIONALLICENCE 700 1- Gainutdinova T. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut NATIONALLICENCE 700 1- Golubev A. Department of Invertebrate Zoology, Kazan' State University, 18 Kremlevskaya Street, 420008, Kazan', Russia aut NATIONALLICENCE 700 1- Muranova L. Biophysics Laboratory, Kazan' Physicotechnical Institute, Russian Academy of Sciences, 10/7 Sibirskii Tract, 420029, Kazan', Russia aut NATIONALLICENCE 773 0- Neuroscience and Behavioral Physiology Kluwer Academic Publishers-Consultants Bureau 35/3(2005-03-01), 305-311 0097-0549 35:3<305 2005 35 11055 NATIONALLICENCE 856 40 https://doi.org/10.1007/s11055-005-0063-8 text/html Onlinezugriff via DOI Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE NATIONALLICENCE NL-springer