caa a22 4500 467945292 CHVBK 20180323165700.0 cr unu---uuuuu 170328e19880901xx s 000 0 eng 10.1007/BF00939305 doi (NATIONALLICENCE)springer-10.1007/BF00939305 (NATIONALLICENCE)springer-10.1007/BF01982900 Fermentation process diagnosis using a mathematical model [Elektronische Daten] [L. Yerushalmi, B. Volesky, J. Votruba] Summary: Intriguing physiology of a solvent-producing strain ofClostridium acetobutylicum led to the synthesis of a mathematical model of the acetone-butanol fermentation process. The model presented is capable of describing the process dynamics and the culture behavior during a standard and a substandard acetone-butanol fermentation. In addition to the process kinetic parameters, the model includes the culture physiological parameters, such as the cellular membrane permeability and the number of membrane sites for active tansport of sugar. Computer process simulation studies for different culture conditions used the model, and quantitatively pointed out the importance of selected culture parameters that characterize the cell membrane behaviour and play an important role in the control of solvent synthesis by the cell. The theoretical predictions by the new model were confirmed by experimental determination of the cellular membrane permeability. Springer-Verlag, 1988 Yerushalmi L. Biochemical Engineering Research Unit, Department of Chemical Engineering, McGill University, H3A 2A7, Montreal, Canada aut Volesky B. Biochemical Engineering Research Unit, Department of Chemical Engineering, McGill University, H3A 2A7, Montreal, Canada aut Votruba J. Biochemical Engineering Research Unit, Department of Chemical Engineering, McGill University, H3A 2A7, Montreal, Canada aut Applied Microbiology and Biotechnology Springer-Verlag 29/2-3(1988-09-01), 186-197 0175-7598 29:2-3<186 1988 29 253 https://doi.org/10.1007/BF00939305 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00939305 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yerushalmi L. Biochemical Engineering Research Unit, Department of Chemical Engineering, McGill University, H3A 2A7, Montreal, Canada aut NATIONALLICENCE 700 1- Volesky B. Biochemical Engineering Research Unit, Department of Chemical Engineering, McGill University, H3A 2A7, Montreal, Canada aut NATIONALLICENCE 700 1- Votruba J. Biochemical Engineering Research Unit, Department of Chemical Engineering, McGill University, H3A 2A7, Montreal, Canada aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 29/2-3(1988-09-01), 186-197 0175-7598 29:2-3<186 1988 29 253 NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01982900 text/html Onlinezugriff via DOI Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE NATIONALLICENCE NL-springer