caa a22 4500 467945934 CHVBK 20180323165700.0 cr unu---uuuuu 170328e19881001xx s 000 0 eng 10.1007/BF02399602 doi (NATIONALLICENCE)springer-10.1007/BF02399602 (NATIONALLICENCE)springer-10.1007/PL00020497 Genetic determinants of glutamine synthetase in Drosophila melanogaster: A gene for glutamine synthetase I resides in the 21B3-6 region [Elektronische Daten] [Corrado Caggese, Ruggiero Caizzi, Maria Bozzetti, Paolo Barsanti, Ferruccio Ritossa] Recombinational and deletion mapping of electrophoretic variants of the glutamine synthetase I isozyme (GSI) inDrosophila melanogaster locates the gene in the 21B region on the second chromosome. We have conducted a genetic analysis of the region extending cytologically from 21A to 21B4-6. Recessive lethal mutations were generated by ethyl methanesulfonate (EMS) and ethyl nitrosourea (ENU) mutagenesis and by hybrid dysgenesis (HD). These lethals fall into seven functional groups, which were partially ordered by complementation with cytologically defined deficiencies of this region generated by hybrid dysgenesis. Two of the EMS- and two of the ENU-induced lethals fulfill biochemical criteria expected for null alleles of the GSI gene. Plenum Publishing Corporation, 1988 glutamine synthetase I nationallicence genetic mapping nationallicence allozymes nationallicence null alleles nationallicence Drosophila nationallicence Caggese Corrado Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut Caizzi Ruggiero Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut Bozzetti Maria Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut Barsanti Paolo Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut Ritossa Ferruccio Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut Biochemical Genetics Kluwer Academic Publishers-Plenum Publishers 26/9-10(1988-10-01), 571-584 0006-2928 26:9-10<571 1988 26 10528 https://doi.org/10.1007/BF02399602 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02399602 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Caggese Corrado Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Caizzi Ruggiero Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Bozzetti Maria Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Barsanti Paolo Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Ritossa Ferruccio Istituto di Genetica dell'Università, via Amendola 165/A, 70126, Bari, Italy aut NATIONALLICENCE 773 0- Biochemical Genetics Kluwer Academic Publishers-Plenum Publishers 26/9-10(1988-10-01), 571-584 0006-2928 26:9-10<571 1988 26 10528 NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00020497 text/html Onlinezugriff via DOI Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE NATIONALLICENCE NL-springer