caa a22 4500 467948585 CHVBK 20180405193739.0 cr unu---uuuuu 170328e20050101xx s 000 0 eng 10.1007/s10541-005-0049-8 doi (NATIONALLICENCE)springer-10.1007/s10541-005-0049-8 (NATIONALLICENCE)springer-10.1007/PL00021752 Molecular mechanisms of hormonal activity. I. receptors. neuromediators. systems with second messengers [Elektronische Daten] [V. Kulinsky, L. Kolesnichenko] Hormone signal transfer along all of the cell compartments including nucleus is powered by signal transduction systems. Characteristics and importance of hormone receptors, principal components, functional mechanisms, and biological role of different systems with second messengers are described. Considerable examples of the importance of these systems for medicine are adduced. The drugs modifying these systems comprise more than 65% of contemporary medicines. MAIK "Nauka/Interperiodica”, 2005 mechanism of hormone action nationallicence signal transduction system nationallicence receptor nationallicence second messenger nationallicence protein kinase nationallicence GABA : γ-aminobutyric acid nationallicence PM : plasma membrane nationallicence STS : signal transduction system (pathway) nationallicence TF : transcription factor nationallicence GF : growth factor nationallicence CH : circulating hormones nationallicence CBP : CREB-binding protein nationallicence GPCR : G-protein-coupled receptor nationallicence HRE : hormone-reactive element nationallicence Kulinsky V. Department of Biochemistry, Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664003, Irkutsk, Russia aut Kolesnichenko L. Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664003, Irkutsk, Russia aut Biochemistry (Moscow) Nauka/Interperiodica 70/1(2005-01-01), 24-39 0006-2979 70:1<24 2005 70 10541 https://doi.org/10.1007/s10541-005-0049-8 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10541-005-0049-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kulinsky V. Department of Biochemistry, Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664003, Irkutsk, Russia aut NATIONALLICENCE 700 1- Kolesnichenko L. Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664003, Irkutsk, Russia aut NATIONALLICENCE 773 0- Biochemistry (Moscow) Nauka/Interperiodica 70/1(2005-01-01), 24-39 0006-2979 70:1<24 2005 70 10541 NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00021752 text/html Onlinezugriff via DOI Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE NATIONALLICENCE NL-springer