caa a22 4500 467949867 CHVBK 20180323165702.0 cr unu---uuuuu 170328e19880901xx s 000 0 eng 10.1007/BF00939304 doi (NATIONALLICENCE)springer-10.1007/BF00939304 (NATIONALLICENCE)springer-10.1007/BF01982899 Physiological control and process kinetics of clavine alkaloid production by Claviceps purpurea [Elektronische Daten] [Miroslav Flieger, Jaroslav Votruba, Vladimír Křen, Sylvie Pažoutová, Viktor Rylko, Přemysl Sajdl, Zdeněk Reháček] Summary: Kinetic parameters of production of clavine alkaloids were evaluated in twoClaviceps purpurea strains. Mutagenesis brought about enhanced resistance of the biosynthetic system towards alkaloids. Addition of glucose into the fermentation medium altered the zero order kinetics of production to activation-inhibition kinetics. The glucose treatment allowed performance of both "elymoclavine-inhibitionless” and "clavine alkaloid-decompositionless” fermentations if a combination of fermentation and separation units in a closed loop was used. Springer-Verlag, 1988 Flieger Miroslav Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Votruba Jaroslav Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Křen Vladimír Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Pažoutová Sylvie Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Rylko Viktor Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Sajdl Přemysl Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Reháček Zdeněk Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut Applied Microbiology and Biotechnology Springer-Verlag 29/2-3(1988-09-01), 181-185 0175-7598 29:2-3<181 1988 29 253 https://doi.org/10.1007/BF00939304 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00939304 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Flieger Miroslav Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 700 1- Votruba Jaroslav Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 700 1- Křen Vladimír Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 700 1- Pažoutová Sylvie Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 700 1- Rylko Viktor Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 700 1- Sajdl Přemysl Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 700 1- Reháček Zdeněk Institute of Microbiology, Czechoslovak Academy of Sciences, Videňská 1083, CS 14220, Prague 4, Czechoslovakia aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 29/2-3(1988-09-01), 181-185 0175-7598 29:2-3<181 1988 29 253 NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01982899 text/html Onlinezugriff via DOI Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE NATIONALLICENCE NL-springer