caa a22 4500 467979057 CHVBK 20180323112514.0 cr unu---uuuuu 170328e19900701xx s 000 0 eng 10.1007/BF01973468 doi (NATIONALLICENCE)springer-10.1007/BF01973468 Bioavailability of iron and cyanide from oral potassium ferric hexacyanoferrate(II) in humans [Elektronische Daten] [Peter Nielsen, Bernd Dresow, Roland Fischer, Hellmuth Heinrich] After oral administration of 500 mg KFe[Fe(CN)6] labelled with59Fe either in the ferric or ferrous position and with14C in the cyanide group only 0.22% of the FeII and <0.04% of the FeIII were absorbed in three male volunteers. Only 2 mg non-complex bound relabelled cyanide (0.03 mg CN-/kg body wt) were absorbed from 500 mg [14C]KFeHCF, which is about a factor of 20-100 below the lethal dose in humans (0.5-3.5 mg CN-/kg body wt). Therefore, iron(III) hexacyanoferrates(II) can be considered as safe antidotes, i.e. for inhibiting the intestinal absorption of radiocaesium or for accelerating the excretion of already absorbed134/137Cs in the case of a severe nuclear accident. Springer-Verlag, 1990 Radiocaesium nationallicence Hexacyanoferrates(II) nationallicence Cyanide bioavailability nationallicence Iron absorption nationallicence Nielsen Peter Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut Dresow Bernd Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut Fischer Roland Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut Heinrich Hellmuth Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut Archives of Toxicology Springer-Verlag 64/5(1990-07-01), 420-422 0340-5761 64:5<420 1990 64 204 https://doi.org/10.1007/BF01973468 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01973468 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nielsen Peter Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut NATIONALLICENCE 700 1- Dresow Bernd Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut NATIONALLICENCE 700 1- Fischer Roland Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut NATIONALLICENCE 700 1- Heinrich Hellmuth Abteilung Medizinische Biochemie, Physiologisch-Chemisches Institut Universitätskrankenhaus Eppendorf, Martinistrasse 52, 2000, Hamburg 20, Federal Republic of Germany aut NATIONALLICENCE 773 0- Archives of Toxicology Springer-Verlag 64/5(1990-07-01), 420-422 0340-5761 64:5<420 1990 64 204 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer