caa a22 4500 467983321 CHVBK 20180323112524.0 cr unu---uuuuu 170328e19900501xx s 000 0 eng 10.1007/BF00210807 doi (NATIONALLICENCE)springer-10.1007/BF00210807 Localization of the human oncogene SPI1 on chromosome 11, region p11.22 [Elektronische Daten] [Nguyen Van Cong, D. Ray, M. Gross, M. de Tand, J. Frézal, F. Moreau-Gachelin] Summary: Spi1 is an oncogene specifically activated in acute murine erythroleukemias induced by the Friend spleen focus forming virus (SFFV). Three probes were used for the chromosomal assignment of the human SPI1 oncogene: cDb1 and RaB2 correspond respectively to murine Spi1 and human SPI1 cDNA probes; C45a6B probe is a murine genomic DNA sequence located in the Spi1 5′ region and is known as a major SFFV integration site in murine erythroleukemia cells. Somatic hybrid cells enabled cDb1 and RaB2 to be assigned to chromosome 11. The murine C45a6B probe, which is not included in the Spi1 gene, detected a homologous sequence on human chromosome 11. RaB2 was assigned to 11p 11.22 by in situ hybridization. Three human genes known between 11p11 and 11p13 (FSHB, CAT, ACP2) were on murine chromosome 2. Therefore, the localization of human SPI1 on 11p11.22 was consistent with the assignment of the Spi1 oncogene to murine chromosome 2. Springer-Verlag, 1990 Van Cong Nguyen Laboratoire de Cytogénétique et de Génétique Oncologiques URA 126 CNRS, Institut Gustave Roussy, 39 Rue Camille Desmoulins, F-94805, Villejuif Cedex, France aut Ray D. INSERM U-248, Faculté de Médecine Lariboisiére-Saint Louis, 10 Avenue de Verdun, F-75010, Paris, France aut Gross M. Laboratoire de Cytogénétique et de Génétique Oncologiques URA 126 CNRS, Institut Gustave Roussy, 39 Rue Camille Desmoulins, F-94805, Villejuif Cedex, France aut de Tand M. Laboratoire de Cytogénétique et de Génétique Oncologiques URA 126 CNRS, Institut Gustave Roussy, 39 Rue Camille Desmoulins, F-94805, Villejuif Cedex, France aut Frézal J. INSERM U-12, Hôpital des Enfants-Malades, 149 Rue de Sévres, F-75743, Paris Cedex 15, France aut Moreau-Gachelin F. INSERM U-248, Faculté de Médecine Lariboisiére-Saint Louis, 10 Avenue de Verdun, F-75010, Paris, France aut Human Genetics Springer-Verlag 84/6(1990-05-01), 542-546 0340-6717 84:6<542 1990 84 439 https://doi.org/10.1007/BF00210807 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00210807 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Van Cong Nguyen Laboratoire de Cytogénétique et de Génétique Oncologiques URA 126 CNRS, Institut Gustave Roussy, 39 Rue Camille Desmoulins, F-94805, Villejuif Cedex, France aut NATIONALLICENCE 700 1- Ray D. INSERM U-248, Faculté de Médecine Lariboisiére-Saint Louis, 10 Avenue de Verdun, F-75010, Paris, France aut NATIONALLICENCE 700 1- Gross M. Laboratoire de Cytogénétique et de Génétique Oncologiques URA 126 CNRS, Institut Gustave Roussy, 39 Rue Camille Desmoulins, F-94805, Villejuif Cedex, France aut NATIONALLICENCE 700 1- de Tand M. Laboratoire de Cytogénétique et de Génétique Oncologiques URA 126 CNRS, Institut Gustave Roussy, 39 Rue Camille Desmoulins, F-94805, Villejuif Cedex, France aut NATIONALLICENCE 700 1- Frézal J. INSERM U-12, Hôpital des Enfants-Malades, 149 Rue de Sévres, F-75743, Paris Cedex 15, France aut NATIONALLICENCE 700 1- Moreau-Gachelin F. INSERM U-248, Faculté de Médecine Lariboisiére-Saint Louis, 10 Avenue de Verdun, F-75010, Paris, France aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 84/6(1990-05-01), 542-546 0340-6717 84:6<542 1990 84 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer