caa a22 4500 467983542 CHVBK 20180323112525.0 cr unu---uuuuu 170328e19900201xx s 000 0 eng 10.1007/BF00200568 doi (NATIONALLICENCE)springer-10.1007/BF00200568 Nucleolus organizer regions in human lymphocytes as studied with premature chromosome condensation [Elektronische Daten] [Franz Wachtler, Christa Roubicek, Andreas Schedle, Wilhelm Mosgöller, Gerlinde Bretis, Hans Schwarzacher] Summary: Non-stimulated human lymphocytes from peripheral blood usually contain only one ring-shaped nucleolus. Polyethyleneglycol-mediated cell fusion with mitotic Chinese hamster ovary cells induces premature chromosome condensation in human lymphocytes. Subsequent silver staining reveals that more than one nucleolus organizer region (NOR) is silverpositive and frequently participates in the formation of "satellite associations”. It can therefore be concluded that more than one NOR contributes to the ring-shaped nucleoli of lymphocytes in human peripheral blood and that they may be transcriptionally active. During phytohemagglutinin (PHA) stimulation, the number of silver-positive NORs, the number of nucleoli and the number of chromosomes participating in "satellite associations” increase. Springer-Verlag, 1990 Wachtler Franz Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut Roubicek Christa Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut Schedle Andreas Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut Mosgöller Wilhelm Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut Bretis Gerlinde Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut Schwarzacher Hans Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut Human Genetics Springer-Verlag 84/3(1990-02-01), 244-248 0340-6717 84:3<244 1990 84 439 https://doi.org/10.1007/BF00200568 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00200568 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wachtler Franz Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Roubicek Christa Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Schedle Andreas Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Mosgöller Wilhelm Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Bretis Gerlinde Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Schwarzacher Hans Histologisch-Embryologisches Institut, Schwarzspanierstrasse 17, A-1090, Wien, Austria aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 84/3(1990-02-01), 244-248 0340-6717 84:3<244 1990 84 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer