caa a22 4500 467983976 CHVBK 20180323112526.0 cr unu---uuuuu 170328e19900401xx s 000 0 eng 10.1007/BF00195814 doi (NATIONALLICENCE)springer-10.1007/BF00195814 Chromosomal in situ hybridization of a Hodgkin's disease-derived cell line (L540) using DNA probes for TCRA, TCRB, MET, and rRNA [Elektronische Daten] [Christa Fonatsch, Georg Gradl, Ulrike Kolbus, Harald Rieder, Hans Tesch] Summary: The Hodgkin's lymphoma-derived cell line L540, which exhibits multiple marker chromosomes and a genotype characteristic of T-cell origin, showed expression of MET oncogene. L540 was studied by in situ hybridization for chromosomal rearrangements concerning the regions where genes for TCRA and TCRB chains, for MET oncogene, and for rRNA are located. All four genes were demonstrated to be involved in the formation of marker chromosomes. Especially remarkable was the participation of rDNA-bearing regions in two different translocations. Springer-Verlag, 1990 Fonatsch Christa Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut Gradl Georg Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut Kolbus Ulrike Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut Rieder Harald Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut Tesch Hans Medizinische Universitätsklinik I, Joseph-Stelzmann-Strasse 9, 41, Köln, Federal Republic of Germany aut Human Genetics Springer-Verlag 84/5(1990-04-01), 427-434 0340-6717 84:5<427 1990 84 439 https://doi.org/10.1007/BF00195814 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00195814 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fonatsch Christa Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut NATIONALLICENCE 700 1- Gradl Georg Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut NATIONALLICENCE 700 1- Kolbus Ulrike Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut NATIONALLICENCE 700 1- Rieder Harald Institut für Humangenetik, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 1, Lübeck, Federal Republic of Germany aut NATIONALLICENCE 700 1- Tesch Hans Medizinische Universitätsklinik I, Joseph-Stelzmann-Strasse 9, 41, Köln, Federal Republic of Germany aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 84/5(1990-04-01), 427-434 0340-6717 84:5<427 1990 84 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer