caa a22 4500 467984328 CHVBK 20180323112527.0 cr unu---uuuuu 170328e19900101xx s 000 0 eng 10.1007/BF00208940 doi (NATIONALLICENCE)springer-10.1007/BF00208940 Chromosomal damage in peripheral blood lymphocytes of patients treated for testicular cancer [Elektronische Daten] [Eva van den Berg-de Ruiter, Bauke de Jong, Nanno Mulder, Gerard te Meerman, Heimen Schraffordt Koops, Dirk Sleijfer] Summary: We describe the presence of a large number of chromosome aberrations in lymphocytes of 50 patients with testicular cancer. These chromosomal aberrations were not only found in patients treated with chemotherapy but also in untreated patients or in patients after surgery alone. Our results suggest a role for genetic instability in the pathogenesis of testicular cancer. This instability might be a risk factor for the development of secondary malignancies. Springer-Verlag, 1990 van den Berg-de Ruiter Eva Department of Human Genetics, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut de Jong Bauke Department of Human Genetics, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut Mulder Nanno Department of Medical Oncology, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut te Meerman Gerard Department of Human Genetics, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut Schraffordt Koops Heimen Department of Surgical Oncology, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut Sleijfer Dirk Department of Medical Oncology, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut Human Genetics Springer-Verlag 84/2(1990-01-01), 191-194 0340-6717 84:2<191 1990 84 439 https://doi.org/10.1007/BF00208940 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00208940 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van den Berg-de Ruiter Eva Department of Human Genetics, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut NATIONALLICENCE 700 1- de Jong Bauke Department of Human Genetics, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut NATIONALLICENCE 700 1- Mulder Nanno Department of Medical Oncology, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut NATIONALLICENCE 700 1- te Meerman Gerard Department of Human Genetics, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut NATIONALLICENCE 700 1- Schraffordt Koops Heimen Department of Surgical Oncology, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut NATIONALLICENCE 700 1- Sleijfer Dirk Department of Medical Oncology, State University, Antonius Deusinglaan 4, NL-9713, AW Groningen, The Netherlands aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 84/2(1990-01-01), 191-194 0340-6717 84:2<191 1990 84 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer