caa a22 4500 467984468 CHVBK 20180323112527.0 cr unu---uuuuu 170328e19900601xx s 000 0 eng 10.1007/BF00276341 doi (NATIONALLICENCE)springer-10.1007/BF00276341 Failure to document fetal cells in maternal circulation using the Selypes-Lorencz "air-culture” cytogenetic technique [Elektronische Daten] [Mounira Youssef, Lee Shulman, Avirachan Tharapel, Joe Simpson, Sherman Elias] Summary: Isolating and analyzing fetal cells circulating in the maternal circulation would allow a relatively noninvasive method (i.e., venipuncture) for prenatal cytogenetic diagnosis. Several groups have claimed evidence for the presence of fetal cells in maternal circulation, and in one communication, Selypes and Lorencz (1988) reported the presence of relatively large numbers of fetal mitotic cells in phytohemagglutinin-stimulated blood cultures derived from pregnant women. We employed the laboratory method of Selypes and Lorencz in evaluating maternal blood from 29 patients (9.7 to 19.5 weeks gestation) in which the fetal complement differed from that of the mother (e.g., 46,XY, aneuploidy). Unfortunately, we were unable to confirm the results of Selypes and Lorencz. Springer-Verlag, 1990 Youssef Mounira Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut Shulman Lee Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut Tharapel Avirachan Department of Pediatrics, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut Simpson Joe Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut Elias Sherman Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut Human Genetics Springer-Verlag 85/1(1990-06-01), 133-134 0340-6717 85:1<133 1990 85 439 https://doi.org/10.1007/BF00276341 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00276341 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Youssef Mounira Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut NATIONALLICENCE 700 1- Shulman Lee Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut NATIONALLICENCE 700 1- Tharapel Avirachan Department of Pediatrics, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut NATIONALLICENCE 700 1- Simpson Joe Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut NATIONALLICENCE 700 1- Elias Sherman Department of Obstetrics and Gynecology, University of Tennessee at Memphis, 853 Jefferson Avenue, 38163, Memphis, TN, USA aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 85/1(1990-06-01), 133-134 0340-6717 85:1<133 1990 85 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer