caa a22 4500 467985359 CHVBK 20180323112530.0 cr unu---uuuuu 170328e19900901xx s 000 0 eng 10.1007/BF02428297 doi (NATIONALLICENCE)springer-10.1007/BF02428297 Frequency of the ΔF508 mutation on cystic fibrosis chromosomes in Denmark [Elektronische Daten] [Marianne Schwartz, Helle Johansen, Christian Koch, Niels Brandt] Summary: We have investigated the frequency of the ΔF508 mutation on cystic fibrosis (CF) chromosomes in Denmark. Of 304 chromosome tested, 86.8% have the ΔF508 mutation. The majority of the chromosomes with this mutation are found on chromosomes with the XV2c/KM19 haplotype B (97.3%), whereas 15/16 chromosomes with haplotype C have another mutation, confirming that only very few mutations will account for the majority of CF genes in the Danish population. Springer-Verlag, 1990 Schwartz Marianne Section of Clinical Genetics Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut Johansen Helle The Danish CF Centre, Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut Koch Christian The Danish CF Centre, Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut Brandt Niels Section of Clinical Genetics Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut Human Genetics Springer-Verlag 85/4(1990-09-01), 427-428 0340-6717 85:4<427 1990 85 439 https://doi.org/10.1007/BF02428297 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02428297 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schwartz Marianne Section of Clinical Genetics Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut NATIONALLICENCE 700 1- Johansen Helle The Danish CF Centre, Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut NATIONALLICENCE 700 1- Koch Christian The Danish CF Centre, Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut NATIONALLICENCE 700 1- Brandt Niels Section of Clinical Genetics Department of Pediatrics, University Hospital, Rigshopitalet 4062, Blegdamsvej 9, DK-2100, Ø Copenhagen, Denmark aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 85/4(1990-09-01), 427-428 0340-6717 85:4<427 1990 85 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer