caa a22 4500 467985480 CHVBK 20180323112530.0 cr unu---uuuuu 170328e19900901xx s 000 0 eng 10.1007/BF02428301 doi (NATIONALLICENCE)springer-10.1007/BF02428301 ΔF508 frequency and associated haplotypes near the cystic fibrosis locus in the Yugoslav population [Elektronische Daten] [Lidija Simova, Carolyn Williams, Georgi Efremov, Aleksandra Gordova-Muratovska, Stojka Suštić, Eila Watson, Robert Williamson] Summary: Chromosomes from 19 unrelated Southern Yugoslav families in which cystic fibrosis (CF) occurs were analysed for the presence of the ΔF508 mutation, using polymerase chain reaction amplification followed by dot blot and polyacrylamide gel analysis. Of the 38 CF chromosomes, 15 (39.5%) carry the ΔF508 deletion. Restriction fragment length polymorphism haplotypes for KM19/PstI, XV2c/TaqI and J3.11/PstI marker loci were determined and are compared for a total of 34 N and 37 CF chromosomes. Springer-Verlag, 1990 Simova Lidija Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut Williams Carolyn Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut Efremov Georgi Research Center for New Technologies, Macedonian Academy of Sciences and Arts, Krste Misirkov bb, YU-91000, Skopje, Yugoslavia aut Gordova-Muratovska Aleksandra Department of Pediatrics, Faculty of Medicine, Vodnjanska, YU-91000, Skopje, Yugoslavia aut Suštić Stojka Department of Pediatrics, Faculty of Medicine, Vodnjanska, YU-91000, Skopje, Yugoslavia aut Watson Eila Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut Williamson Robert Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut Human Genetics Springer-Verlag 85/4(1990-09-01), 432-433 0340-6717 85:4<432 1990 85 439 https://doi.org/10.1007/BF02428301 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02428301 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Simova Lidija Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut NATIONALLICENCE 700 1- Williams Carolyn Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut NATIONALLICENCE 700 1- Efremov Georgi Research Center for New Technologies, Macedonian Academy of Sciences and Arts, Krste Misirkov bb, YU-91000, Skopje, Yugoslavia aut NATIONALLICENCE 700 1- Gordova-Muratovska Aleksandra Department of Pediatrics, Faculty of Medicine, Vodnjanska, YU-91000, Skopje, Yugoslavia aut NATIONALLICENCE 700 1- Suštić Stojka Department of Pediatrics, Faculty of Medicine, Vodnjanska, YU-91000, Skopje, Yugoslavia aut NATIONALLICENCE 700 1- Watson Eila Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut NATIONALLICENCE 700 1- Williamson Robert Regional DNA Laboratory, St. Mary's Hospital Medical School, Norfolk Place, W2 1PG, London, UK aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 85/4(1990-09-01), 432-433 0340-6717 85:4<432 1990 85 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer