caa a22 4500 467985529 CHVBK 20180323112530.0 cr unu---uuuuu 170328e19900901xx s 000 0 eng 10.1007/BF02428290 doi (NATIONALLICENCE)springer-10.1007/BF02428290 The haplotype distribution of the ΔF508 mutation in cystic fibrosis families in Scotland [Elektronische Daten] [Iain McIntosh, Ann Curtis, Maria-Luz Lorenzo, Marion Keston, Annette Gilfillan, Gillian Morris, David Brock] Summary: The gene defective in cystic fibrosis (CF) has recently been isolated and the major mutation identified. The haplotype distribution of this mutation (ΔF508) has been determined for 215 CF chromosomes in the Scottish population. ΔF508 represents 73% of all CF mutations in this group. There remains considerable linkage disequilibrium between XV2c and KM19 and other mutations in the CF gene. Springer-Verlag, 1990 McIntosh Iain Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut Curtis Ann Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut Lorenzo Maria-Luz Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut Keston Marion Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut Gilfillan Annette Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut Morris Gillian Duncan Guthrie Institute of Medical Genetics, G3 8SJ, Yorkhill, Glasgow, UK aut Brock David Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut Human Genetics Springer-Verlag 85/4(1990-09-01), 419-420 0340-6717 85:4<419 1990 85 439 https://doi.org/10.1007/BF02428290 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02428290 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McIntosh Iain Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut NATIONALLICENCE 700 1- Curtis Ann Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut NATIONALLICENCE 700 1- Lorenzo Maria-Luz Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut NATIONALLICENCE 700 1- Keston Marion Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut NATIONALLICENCE 700 1- Gilfillan Annette Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut NATIONALLICENCE 700 1- Morris Gillian Duncan Guthrie Institute of Medical Genetics, G3 8SJ, Yorkhill, Glasgow, UK aut NATIONALLICENCE 700 1- Brock David Human Genetics Unit, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 85/4(1990-09-01), 419-420 0340-6717 85:4<419 1990 85 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer