caa a22 4500 467986134 CHVBK 20180323112532.0 cr unu---uuuuu 170328e19900701xx s 000 0 eng 10.1007/BF00193193 doi (NATIONALLICENCE)springer-10.1007/BF00193193 Centromere splitting in bladder cancer [Elektronische Daten] [Georgina Berrozpe, Maria Caballin, Rosa Miró, A. Gelabert, José Egozcue] Summary: Cytogenetic studies on a bladder carcinoma, carried out using short time cultures, showed centromere splitting (CS) mainly affecting chromosomes 22, 13, 14, 21, 15, 20, 12, 7, 17, and 18. Clonal trisomies and monosomies were also detected. Our case is the first description of CS in bladder tumor cells. Our results suggest that CS is an early phenomenon in the karyotypic evolution of this case; it can be considered a primary, yet unspecific, chromosome change related to aneuploidy in bladder cancer. Springer-Verlag, 1990 Berrozpe Georgina Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut Caballin Maria Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut Miró Rosa Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut Gelabert A. Servei d'Urologia Hospital del Mar, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut Egozcue José Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut Human Genetics Springer-Verlag 85/2(1990-07-01), 184-186 0340-6717 85:2<184 1990 85 439 https://doi.org/10.1007/BF00193193 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00193193 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Berrozpe Georgina Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut NATIONALLICENCE 700 1- Caballin Maria Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut NATIONALLICENCE 700 1- Miró Rosa Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut NATIONALLICENCE 700 1- Gelabert A. Servei d'Urologia Hospital del Mar, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut NATIONALLICENCE 700 1- Egozcue José Institut de Biologia Fonamental "Vicent Villar Palasí”, Universitat Autònoma de Barcelona, Campus Universitari, E-08193, Bellaterra, Spain aut NATIONALLICENCE 773 0- Human Genetics Springer-Verlag 85/2(1990-07-01), 184-186 0340-6717 85:2<184 1990 85 439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer