caa a22 4500 467987556 CHVBK 20180323112536.0 cr unu---uuuuu 170328e19900601xx s 000 0 eng 10.1007/BF02539044 doi (NATIONALLICENCE)springer-10.1007/BF02539044 Microbial contamination and sick building syndrome [Elektronische Daten] [Olivier Michel, Roberta Ginanni] Summary: Permanence within a building is frequently associated with health complaints identified as several clinical syndromes. Contamination by bacterial products may play a predominant role in some of these clinical syndromes, like building-related asthma, humidifier fever or the sick building syndrome (SBS). Indeed, on one side, in air-conditioned systems, the physical conditions are optimal for microbial development and for endotoxin production (from the membrane of gram negative bacteria) and on the other side, inhalation of endotoxin has demonstrated the onset of a bronchial obstruction and an increase in airway reactivity leading to non specific chest complaints. Nevertheless, this hypothesis on aetiopathogenesis of SBS remains to be demonstrated by environmental and lung functional studies on the building site. Kluwer Academic Publishers, 1990 endotoxin nationallicence non specific bronchial responsiveness nationallicence sick building syndrome nationallicence Michel Olivier Clinic of Allergology and Respiratory Diseases, St Pierre University Hospital, Rue Haute 322, 1000, B-Brussels aut Ginanni Roberta Clinic of Allergology and Respiratory Diseases, St Pierre University Hospital, Rue Haute 322, 1000, B-Brussels aut Aerobiologia Kluwer Academic Publishers 6/1(1990-06-01), 51-53 0393-5965 6:1<51 1990 6 10453 https://doi.org/10.1007/BF02539044 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02539044 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Michel Olivier Clinic of Allergology and Respiratory Diseases, St Pierre University Hospital, Rue Haute 322, 1000, B-Brussels aut NATIONALLICENCE 700 1- Ginanni Roberta Clinic of Allergology and Respiratory Diseases, St Pierre University Hospital, Rue Haute 322, 1000, B-Brussels aut NATIONALLICENCE 773 0- Aerobiologia Kluwer Academic Publishers 6/1(1990-06-01), 51-53 0393-5965 6:1<51 1990 6 10453 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer