caa a22 4500 467990948 CHVBK 20180323112544.0 cr unu---uuuuu 170328e19900601xx s 000 0 eng 10.1007/BF00756423 doi (NATIONALLICENCE)springer-10.1007/BF00756423 Pyrido[2,3-d]pyrimidines. 1. Acylation of 2,4,5-trioxo-7-amino-8H-pyrido [2,3-d]pyrimidines [Elektronische Daten] [O. Burova, N. Smirnova, T. Safonova] Reaction of 2,4,5-trioxo-7-aminopyrido[2,3-d]pyrimidines with acylating agents takes place both at the amino group and at the cyclic nitrogen atom. Reaction of these compounds with formic acid, chloroacetyl chloride in pyridine, cyanoacetic acid in the presence of acetic anhydride, and oxalyl chloride leads to monoacylation at the amino group but with methyl chloroformate it is the product of acylation at the cyclic nitrogen. Refluxing in acetic anhydride gave mono-, di-, and triacetyl derivatives. The structures of these compounds were proved using spectral data. Plenum Publishing Corporation, 1990 Burova O. Novosibirsk Chemicopharmaceutical Science Research Institute, 654034, Novosibirsk aut Smirnova N. Novosibirsk Chemicopharmaceutical Science Research Institute, 654034, Novosibirsk aut Safonova T. Novosibirsk Chemicopharmaceutical Science Research Institute, 654034, Novosibirsk aut Chemistry of Heterocyclic Compounds Kluwer Academic Publishers-Plenum Publishers 26/6(1990-06-01), 677-680 0009-3122 26:6<677 1990 26 10593 https://doi.org/10.1007/BF00756423 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00756423 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Burova O. Novosibirsk Chemicopharmaceutical Science Research Institute, 654034, Novosibirsk aut NATIONALLICENCE 700 1- Smirnova N. Novosibirsk Chemicopharmaceutical Science Research Institute, 654034, Novosibirsk aut NATIONALLICENCE 700 1- Safonova T. Novosibirsk Chemicopharmaceutical Science Research Institute, 654034, Novosibirsk aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Kluwer Academic Publishers-Plenum Publishers 26/6(1990-06-01), 677-680 0009-3122 26:6<677 1990 26 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer