caa a22 4500 46799546X CHVBK 20180323112556.0 cr unu---uuuuu 170328e19900101xx s 000 0 eng 10.1007/BF01244288 doi (NATIONALLICENCE)springer-10.1007/BF01244288 Solvent-generated HPLC systems with β-cyclodextrin derivatives as chiral additives [Elektronische Daten] [Maria Pawłowska, Janusz Zukowski] It is shown that enantioselective solvent-generated liquid-liquid and liquid-solid Chromatographic systems with β-cyclodextrin derivatives can be realized. The liquid-liquid systems are based on ternary solvent systems of limited miscibility, containing chiral additives; the chiral stationary phase is spontaneously generated on the porous microparticulate silica used as a solid support. In the solvent-generated adsorption systems a very small proportion of β-cyclodextrin derivatives is added to the mobile phase. These components act as column activators, since they are strongly adsorbed on the RP solid support where they form new stereoselective adsorption sites. It is demonstrated that dynamically generated systems with β-cyclodextrin derivatives as chiral agents are powerful and versatile tools for enantioseparation of different types of compounds. This technique creates not only a new type of selectivity but also leads to very stable and reproducible Chromatographic columns. Springer-Verlag, 1990 solvent-generated HPLC systems nationallicence enantiomeric resolution nationallicence Pawłowska Maria Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44, PL-01-224, Warsaw, Poland aut Zukowski Janusz Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44, PL-01-224, Warsaw, Poland aut Microchimica Acta Springer-Verlag 102/1-3(1990-01-01), 55-69 0026-3672 102:1-3<55 1990 102 604 https://doi.org/10.1007/BF01244288 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01244288 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pawłowska Maria Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44, PL-01-224, Warsaw, Poland aut NATIONALLICENCE 700 1- Zukowski Janusz Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44, PL-01-224, Warsaw, Poland aut NATIONALLICENCE 773 0- Microchimica Acta Springer-Verlag 102/1-3(1990-01-01), 55-69 0026-3672 102:1-3<55 1990 102 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer