caa a22 4500 467996091 CHVBK 20180323112557.0 cr unu---uuuuu 170328e19900901xx s 000 0 eng 10.1007/BF01242888 doi (NATIONALLICENCE)springer-10.1007/BF01242888 Determination of phenytoin by modified extraction-gravimetry with a piezoelectric transducer [Elektronische Daten] [Li Nie, Xiao Zhang, Shou Yao] An extraction-frequencymetric method has been proposed for the determination of phenytoin sodium using a newly developed ring-coated piezoelectric crystal transducer. The sample solution is acidified with HCl and the liberated free phenytoin is extracted with 1,2-dichloroethane. The extract is applied to a ring-coated quartz crystal in nitrogen stream and after 2 min the crystal frequency is measured. The frequency change due to the deposited phenytoin is proportional to the phenytoin sodium content in the range 0.02-1.2 μg. The method can be applied to the assay of phenytoin sodium tablets and injections. Springer-Verlag, 1990 phenytoin nationallicence piezoelectric transducer nationallicence extraction nationallicence Nie Li Department of Chemical Engineering, Institute for New Material Research, Hunan University, 410012, Changsha, People's Republic of China aut Zhang Xiao Department of Chemical Engineering, Institute for New Material Research, Hunan University, 410012, Changsha, People's Republic of China aut Yao Shou Department of Chemical Engineering, Institute for New Material Research, Hunan University, 410012, Changsha, People's Republic of China aut Microchimica Acta Springer-Verlag 100/5-6(1990-09-01), 287-292 0026-3672 100:5-6<287 1990 100 604 https://doi.org/10.1007/BF01242888 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01242888 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nie Li Department of Chemical Engineering, Institute for New Material Research, Hunan University, 410012, Changsha, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Xiao Department of Chemical Engineering, Institute for New Material Research, Hunan University, 410012, Changsha, People's Republic of China aut NATIONALLICENCE 700 1- Yao Shou Department of Chemical Engineering, Institute for New Material Research, Hunan University, 410012, Changsha, People's Republic of China aut NATIONALLICENCE 773 0- Microchimica Acta Springer-Verlag 100/5-6(1990-09-01), 287-292 0026-3672 100:5-6<287 1990 100 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer