caa a22 4500 467996288 CHVBK 20180323112558.0 cr unu---uuuuu 170328e19900101xx s 000 0 eng 10.1007/BF01244506 doi (NATIONALLICENCE)springer-10.1007/BF01244506 Extraction-spectrophotometric determination of some antihistaminic agents with fast green FCF [Elektronische Daten] [Chilukuri Sastry, Tipirneni Prasad, Mulukutla Suryanarayana] A rapid, simple, precise, accurate and highly sensitive method for the determination of some antihistaminic agents such as dimethindene maleate (DMM), embramine hydrochloride (EMH), isothipendyl hydrochloride (IPH), mebhydrolin napadisylate (MHn), methdilazine hydrochloride (MDH), promethazine hydrochloride (PMH), trimeprazine tartrate (TMT) and triprolidine hydrochloride (TPH) in bulk samples and pharmaceutical preparations is proposed. The method is based on the formation of a chloroform-soluble ion-association complex between the antihistaminic agent and Fast Green FCF at pH 5.0 with an absorption maximum at 620 nm. The composition of antihistaminic agent and Fast Green FCF in each ion-association complex is studied. The relative standard deviation of the proposed method is less than 1.3%, the percent recovery is 99.4-100.2% and the results are not significantly different from the standard methods at the 95% confidence level. Springer-Verlag, 1990 extraction nationallicence spectrophotometry nationallicence antihistaminic agent nationallicence Fast Green FCF nationallicence pharmaceutical preparations nationallicence Sastry Chilukuri Food and Drug Laboratories, School of Chemistry, Andhra University, 530 003, Waltair, India aut Prasad Tipirneni Food and Drug Laboratories, School of Chemistry, Andhra University, 530 003, Waltair, India aut Suryanarayana Mulukutla Food and Drug Laboratories, School of Chemistry, Andhra University, 530 003, Waltair, India aut Microchimica Acta Springer-Verlag 100/1-2(1990-01-01), 107-112 0026-3672 100:1-2<107 1990 100 604 https://doi.org/10.1007/BF01244506 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01244506 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sastry Chilukuri Food and Drug Laboratories, School of Chemistry, Andhra University, 530 003, Waltair, India aut NATIONALLICENCE 700 1- Prasad Tipirneni Food and Drug Laboratories, School of Chemistry, Andhra University, 530 003, Waltair, India aut NATIONALLICENCE 700 1- Suryanarayana Mulukutla Food and Drug Laboratories, School of Chemistry, Andhra University, 530 003, Waltair, India aut NATIONALLICENCE 773 0- Microchimica Acta Springer-Verlag 100/1-2(1990-01-01), 107-112 0026-3672 100:1-2<107 1990 100 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer