caa a22 4500 469026332 CHVBK 20180323132731.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF01962692 doi (NATIONALLICENCE)springer-10.1007/BF01962692 Centralized preparation of hazardous drugs [Elektronische Daten] A choice between isolator and laminar airflow [P. Larrouturou, J. Huchet, M. Taugourdeau] In 1987, the manager of the Saint-Joseph Hospital (Paris, France) requested a reorganization of cytotoxic drug preparation. Protection for staff who handle hazardous drugs was the main concern. The conclusions drawn from a first analysis emphasize the advantages of a centralized reconstitution unit against a decentralized system. Subsequently, a workload study and an economic study (investment, maintenance, supplies, staff costs, comparative balance sheet and a 5-year simulation) were carried out, but to choose between a laminar airflow in aseptic room and an isolator in a conventional room. The selected isolator is the first of the conception: the central half-suit uses as a server, and four sleeves located on one side allow two technicians to work in a sterile and closed area without sterile garments. Royal Dutch Association for Advancement of Pharmacy, 1992 Antineoplastic agents nationallicence Cost and cost analysis nationallicence Drug compounding nationallicence Equipment and supplies nationallicence Isolator nationallicence Laminar airflow hood nationallicence Larrouturou P. Department of Pharmacy, Saint-Joseph Hospital, 7 Rue Pierre Larousse, 75674, Paris Cedex, France aut Huchet J. Department of Pharmacy, Saint-Joseph Hospital, 7 Rue Pierre Larousse, 75674, Paris Cedex, France aut Taugourdeau M. Department of Pharmacy, Saint-Joseph Hospital, 7 Rue Pierre Larousse, 75674, Paris Cedex, France aut Pharmaceutisch Weekblad Kluwer Academic Publishers 14/3(1992-06-01), 88-92 0031-6911 14:3<88 1992 14 11096 https://doi.org/10.1007/BF01962692 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01962692 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Larrouturou P. Department of Pharmacy, Saint-Joseph Hospital, 7 Rue Pierre Larousse, 75674, Paris Cedex, France aut NATIONALLICENCE 700 1- Huchet J. Department of Pharmacy, Saint-Joseph Hospital, 7 Rue Pierre Larousse, 75674, Paris Cedex, France aut NATIONALLICENCE 700 1- Taugourdeau M. Department of Pharmacy, Saint-Joseph Hospital, 7 Rue Pierre Larousse, 75674, Paris Cedex, France aut NATIONALLICENCE 773 0- Pharmaceutisch Weekblad Kluwer Academic Publishers 14/3(1992-06-01), 88-92 0031-6911 14:3<88 1992 14 11096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer