caa a22 4500 469030135 CHVBK 20180323132741.0 cr unu---uuuuu 170328e19920101xx s 000 0 eng 10.1007/BF01043281 doi (NATIONALLICENCE)springer-10.1007/BF01043281 Mitochondrial carbonic anhydrase in osteoclasts and two different epithelial acid-secreting cells [Elektronische Daten] [Eeva-Kaisa Karhukorpi, Päivi Lakkakorpi, Nicholas Carter, Susan Dodgson, Kalervo Väänänen] Summary: Acid secreting cells are rich in mitochondria and contain high levels of cytoplasmic carbonic anhydrase II. We have studied the ultrastructural distribution of a mitochondrial isoenzyme, carbonic anhydrase V, in two different acid-secreting epithelial cells, gastric parietal cells and kidney intercalated cells as well as in osteoclasts, which are the main bone resorbing cells. The mitochondria differ in carbonic anhydrase V content in these three acid-producing cells: gastric parietal cell mitochondria show strong immunolabelling for this isoenzyme, osteoclast mitochondria faint labelling and kidney intercalated cell mitochondria no labelling. The immunolabelling was located in the mitochondrial matrix, often in close contact with the inner mitochondrial membrane. These results show that mitochondrial carbonic anhydrase levels are not related to acid-transporting activity. Chapman & Hall, 1992 Karhukorpi Eeva-Kaisa Department of Anatomy, University of Oulu, Kajaanintie 52A, SF-90220, Oulu, Finland aut Lakkakorpi Päivi Department of Anatomy, University of Oulu, Kajaanintie 52A, SF-90220, Oulu, Finland aut Carter Nicholas Department of Child Health, St. Georges Hospital, Medical School, University of London, SW 17 ORE, UK aut Dodgson Susan Department of Physiology, University of Pennsylvania, Philadelphia, USA aut Väänänen Kalervo Department of Anatomy, University of Oulu, Kajaanintie 52A, SF-90220, Oulu, Finland aut The Histochemical Journal Kluwer Academic Publishers 24/1(1992-01-01), 9-14 0018-2214 24:1<9 1992 24 10735 https://doi.org/10.1007/BF01043281 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01043281 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Karhukorpi Eeva-Kaisa Department of Anatomy, University of Oulu, Kajaanintie 52A, SF-90220, Oulu, Finland aut NATIONALLICENCE 700 1- Lakkakorpi Päivi Department of Anatomy, University of Oulu, Kajaanintie 52A, SF-90220, Oulu, Finland aut NATIONALLICENCE 700 1- Carter Nicholas Department of Child Health, St. Georges Hospital, Medical School, University of London, SW 17 ORE, UK aut NATIONALLICENCE 700 1- Dodgson Susan Department of Physiology, University of Pennsylvania, Philadelphia, USA aut NATIONALLICENCE 700 1- Väänänen Kalervo Department of Anatomy, University of Oulu, Kajaanintie 52A, SF-90220, Oulu, Finland aut NATIONALLICENCE 773 0- The Histochemical Journal Kluwer Academic Publishers 24/1(1992-01-01), 9-14 0018-2214 24:1<9 1992 24 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer