caa a22 4500 469030208 CHVBK 20180323132741.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF01046166 doi (NATIONALLICENCE)springer-10.1007/BF01046166 Studies on the distribution of calcitonin gene-related peptide-like and substance P-like immunoreactivities in rat hind limb muscles [Elektronische Daten] [S. Forsgren, A. Bergh, E. Carlsson, L. Thornell] Summary: The tibialis anterior, extensor digitorum longus and soleus muscles in the rat were examined with respect to the presence of calcitonin gene-related peptide-like as well as substance P-like immunoreactivity. In some of the motor endplates in these muscles, identified by staining for acetylcholinesterase activity, calcitonin gene-related peptide-like immunoreactivity was detected, but in others it was not. Calcitonin gene-related peptide-like immunoreactivity was found to coexist with substance-P-like immunoreactivity in nerve fibres located outside and inside the capsule of the muscle spindles, as well as in nerve fibres located in nerve fascicles. These fibres presumably represent sensory nerve fibres. Calcitonin gene-related peptide-like immunoreactivity, but not substance P-like immunoreactivity, was also detected, in cap-like structures located on the surface of the intrafusal muscle fibres in the polar regions of the spindles, structures which are likely to correspond to motor plate endings. The observations suggest that calcitonin gene-related peptide is heterogeneously present in the endplates of rat hind limb muscles, and gives for the first time immunohistochemical evidence for the presence of calcitonin gene-related peptide and substance P in the innervation of muscle spindles. Chapman & Hall, 1992 Forsgren S. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut Bergh A. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut Carlsson E. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut Thornell L. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut The Histochemical Journal Kluwer Academic Publishers 24/6(1992-06-01), 345-353 0018-2214 24:6<345 1992 24 10735 https://doi.org/10.1007/BF01046166 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01046166 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Forsgren S. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut NATIONALLICENCE 700 1- Bergh A. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut NATIONALLICENCE 700 1- Carlsson E. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut NATIONALLICENCE 700 1- Thornell L. Department of Anatomy, University of Umeå, S-90187, Umeå, Sweden aut NATIONALLICENCE 773 0- The Histochemical Journal Kluwer Academic Publishers 24/6(1992-06-01), 345-353 0018-2214 24:6<345 1992 24 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer