caa a22 4500 469030305 CHVBK 20180323132741.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF01046168 doi (NATIONALLICENCE)springer-10.1007/BF01046168 An immunohistochemical study of the catecholamine synthesizing enzymes and neuropeptides in the female guinea-pig uterus and vagina [Elektronische Daten] [B. Mitchell, E. Ahmed] Summary: The uterus and vagina of the guinea pig have been examined, region by region, for acetylcholinesterase, tyrosine hydroxylase, dopamine β-hydroxylase and aromatic amino acid decarboxylase activity, as well as for the neuropeptides, neuropeptide Y, vasoactive intestinal peptide, substance P, enkephalin and somatostatin. No acetylcholinesterase activity was localized in the uterus, though it was present in associated paracervical ganglion tissues. Of the catecholamine-synthesizing enzymes, tyrosine hydroxylase and dopamine β-hydroxylase activity was found virtually throughout the reproductive tract, whereas aromatic amino acid decarboxylase activity was restricted in its distribution. Neuropeptide distribution was quite varied. Neuropeptide Y was found throughout the endometrium/submucosa but only in the muscularis of the vagina and not in the myometrium. Substance P was localized in the vagina and uterine horn, though not the body of the uterus. Vasoactive intestinal peptide was present in all regions of the endometrium/submucosa, but not in the myometrium of the uterine horn. Enkephalin and somatostatin were not localized in any part of the reproductive tract examined, apart from paracervical ganglion tissues. The types and significance of the nerves supplying the reproductive tract are discussed. Chapman & Hall, 1992 Mitchell B. Human Morphology, Faculty of Medicine, University of Southampton, Biomedical Sciences Building, SO9 3TU, Southampton, UK aut Ahmed E. Human Morphology, Faculty of Medicine, University of Southampton, Biomedical Sciences Building, SO9 3TU, Southampton, UK aut The Histochemical Journal Kluwer Academic Publishers 24/6(1992-06-01), 361-367 0018-2214 24:6<361 1992 24 10735 https://doi.org/10.1007/BF01046168 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01046168 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mitchell B. Human Morphology, Faculty of Medicine, University of Southampton, Biomedical Sciences Building, SO9 3TU, Southampton, UK aut NATIONALLICENCE 700 1- Ahmed E. Human Morphology, Faculty of Medicine, University of Southampton, Biomedical Sciences Building, SO9 3TU, Southampton, UK aut NATIONALLICENCE 773 0- The Histochemical Journal Kluwer Academic Publishers 24/6(1992-06-01), 361-367 0018-2214 24:6<361 1992 24 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer