caa a22 4500 46903033X CHVBK 20180323132741.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF01047587 doi (NATIONALLICENCE)springer-10.1007/BF01047587 Prostaglandin E2 localization in the rat ileum [Elektronische Daten] [Elsa Schmauder-Chock, Stephen Chock] Summary: The application of anti-prostaglandin E2 immunoglobulin to plastic-embedded thin sections of the rat ileum has permitted the localization of prostaglandin E2 in this tissue. In agreement with the published data (Chock & Schmauder-Chock (1988), Schmauder-Chock & Chock (1989)), the results also suggest the presence of an arachidonic acid cascade in the granules of various secretory cells of the gut. Since antibody labelling was found within the secretory granules of connective tissue mast cells, goblet cells, and Paneth cells, the presence of the arachidonic acid cascade in these granules is implied. The appearance of prostaglandin E2 over the non-cellular internal elastic lamina of arterioles suggests that it may have been secreted along with the elastin. The even distribution of prostaglandin throughout the cytoplasm of the erythrocyte is consistent with the concept that this cell scavenges the eicosanoid from the circulation. These data further link the secretorh granule to the production of eicosanoids and therefore illustrate the potential sources of prostaglandins in the rat ileum. Chapman & Hall, 1992 Schmauder-Chock Elsa Department of Experimental Hematology, Armed Forces Radiobiology Research Institute, 20814-5145, Bethesda, MD, USA aut Chock Stephen Department of Experimental Hematology, Armed Forces Radiobiology Research Institute, 20814-5145, Bethesda, MD, USA aut The Histochemical Journal Kluwer Academic Publishers 24/9(1992-09-01), 663-672 0018-2214 24:9<663 1992 24 10735 https://doi.org/10.1007/BF01047587 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01047587 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schmauder-Chock Elsa Department of Experimental Hematology, Armed Forces Radiobiology Research Institute, 20814-5145, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Chock Stephen Department of Experimental Hematology, Armed Forces Radiobiology Research Institute, 20814-5145, Bethesda, MD, USA aut NATIONALLICENCE 773 0- The Histochemical Journal Kluwer Academic Publishers 24/9(1992-09-01), 663-672 0018-2214 24:9<663 1992 24 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer