caa a22 4500 469032502 CHVBK 20180323132747.0 cr unu---uuuuu 170328e19920101xx s 000 0 eng 10.1007/BF00216625 doi (NATIONALLICENCE)springer-10.1007/BF00216625 Molecular definition of an elusive third HLA-A9 molecule: HLA-A9.3 [Elektronische Daten] [Ann-Margaret Little, J. Madrigal, Peter Parham] The HLA-A9 family has been characterized as possessing two well defined specificities; HLA-A23 and A24. Serological studies have suggested the presence of a third member of this family HLA-A9.3, however there is doubt surrounding the existence of this specificity. HLA-A23, A24, and the putative A9.3 proteins were analyzed biochemically by immunoprecipitation and isoelectric focusing. Both HLA-A24 and A9.3 have identical isoelectric points whereas A23 is different. We have sequenced cDNA encoding HLA-A23, A24, and A9.3. From the observed protein sequences, we found A9.3 to differ from A24 by two amino acid substitutions located in the α2 helix of the class I molecule. These substitutions are expected to significantly change the shape of the peptide binding cleft. Springer-Verlag, 1992 Little Ann-Margaret Department of Cell Biology, and Microbiology and Immunology, Sherman Fairchild Building, Stanford University School of Medicine, 94305-5400, Stanford, CA, USA aut Madrigal J. Department of Cell Biology, and Microbiology and Immunology, Sherman Fairchild Building, Stanford University School of Medicine, 94305-5400, Stanford, CA, USA aut Parham Peter Department of Cell Biology, and Microbiology and Immunology, Sherman Fairchild Building, Stanford University School of Medicine, 94305-5400, Stanford, CA, USA aut Immunogenetics Springer-Verlag 35/1(1992-01-01), 41-45 0093-7711 35:1<41 1992 35 251 https://doi.org/10.1007/BF00216625 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00216625 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Little Ann-Margaret Department of Cell Biology, and Microbiology and Immunology, Sherman Fairchild Building, Stanford University School of Medicine, 94305-5400, Stanford, CA, USA aut NATIONALLICENCE 700 1- Madrigal J. Department of Cell Biology, and Microbiology and Immunology, Sherman Fairchild Building, Stanford University School of Medicine, 94305-5400, Stanford, CA, USA aut NATIONALLICENCE 700 1- Parham Peter Department of Cell Biology, and Microbiology and Immunology, Sherman Fairchild Building, Stanford University School of Medicine, 94305-5400, Stanford, CA, USA aut NATIONALLICENCE 773 0- Immunogenetics Springer-Verlag 35/1(1992-01-01), 41-45 0093-7711 35:1<41 1992 35 251 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer