caa a22 4500 469032596 CHVBK 20180323132747.0 cr unu---uuuuu 170328e19920401xx s 000 0 eng 10.1007/BF00179793 doi (NATIONALLICENCE)springer-10.1007/BF00179793 The activation of major histocompatibility complex class I genes by interferon regulatory factor-1 (IRF-1) [Elektronische Daten] [Cheong-Hee Chang, Juergen Hammer, Johnson Loh, William Fodor, Richard Flavell] We have investigated the role of interferon regulatory factor-1 (IRF-1), an interferon-γ (IFN-γ) inducible transcriptional activator, on major histocompatibility complex (MHC) class I gene transcription. IRF-1 alone is sufficient to trans-activate both transfected and endogenous class I genes and the effect of IRF-1 appears to be direct and sequence-specific. These data suggest that IRF-1 is involved in the IFN-γ mediated induction of MHC class I expression. Springer-Verlag, 1992 Chang Cheong-Hee Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut Hammer Juergen Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut Loh Johnson Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut Fodor William Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut Flavell Richard Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut Immunogenetics Springer-Verlag 35/6(1992-04-01), 378-384 0093-7711 35:6<378 1992 35 251 https://doi.org/10.1007/BF00179793 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00179793 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chang Cheong-Hee Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut NATIONALLICENCE 700 1- Hammer Juergen Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut NATIONALLICENCE 700 1- Loh Johnson Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut NATIONALLICENCE 700 1- Fodor William Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut NATIONALLICENCE 700 1- Flavell Richard Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA aut NATIONALLICENCE 773 0- Immunogenetics Springer-Verlag 35/6(1992-04-01), 378-384 0093-7711 35:6<378 1992 35 251 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer