caa a22 4500 469032995 CHVBK 20180323132748.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF00189894 doi (NATIONALLICENCE)springer-10.1007/BF00189894 Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198 [Elektronische Daten] [P. Dyson, Charles de Smet, Andrew Knight, Dominique Simon-Chazottes, Jean Guénet, Thierry Boon] Tum - comprises a class of genes, mutation of which in P815 tumor cells has led to the acquisition of new cytotoxic T cell-recognized epitopes. The cells carrying the mutant alleles have impaired tumorigenicity compared with their progenitors due to in vivo induction of a cytotoxic T-cell response specific for tum - antigens. Two tum - genes, P91A and P35B, were found to be single copy loci mapping to chromosomes 11 and 15 respectively. A third, P198, was found to map to chromosome 7 and to be a member of a small gene family with other members on chromosomes 13, 14, and 15. Multiple P198-related sequences were found in other mammalian species suggesting the P198 related gene family is a general feature of mammalian genomes. Springer-Verlag, 1992 Dyson P. Transplantation Biology, Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, UK aut de Smet Charles Ludwig Institute for Cancer Research, Brussels Branch, 74 avenue Hippcrate, UCL 74-59, B-1200, Brussels, Belgium aut Knight Andrew Transplantation Biology, Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, UK aut Simon-Chazottes Dominique Institut Pasteur, 28 rue du Dr. Roux, 75724, Paris Cedex 15, France aut Guénet Jean Institut Pasteur, 28 rue du Dr. Roux, 75724, Paris Cedex 15, France aut Boon Thierry Ludwig Institute for Cancer Research, Brussels Branch, 74 avenue Hippcrate, UCL 74-59, B-1200, Brussels, Belgium aut Immunogenetics Springer-Verlag 35/5(1992-03-01), 316-323 0093-7711 35:5<316 1992 35 251 https://doi.org/10.1007/BF00189894 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00189894 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dyson P. Transplantation Biology, Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, UK aut NATIONALLICENCE 700 1- de Smet Charles Ludwig Institute for Cancer Research, Brussels Branch, 74 avenue Hippcrate, UCL 74-59, B-1200, Brussels, Belgium aut NATIONALLICENCE 700 1- Knight Andrew Transplantation Biology, Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, UK aut NATIONALLICENCE 700 1- Simon-Chazottes Dominique Institut Pasteur, 28 rue du Dr. Roux, 75724, Paris Cedex 15, France aut NATIONALLICENCE 700 1- Guénet Jean Institut Pasteur, 28 rue du Dr. Roux, 75724, Paris Cedex 15, France aut NATIONALLICENCE 700 1- Boon Thierry Ludwig Institute for Cancer Research, Brussels Branch, 74 avenue Hippcrate, UCL 74-59, B-1200, Brussels, Belgium aut NATIONALLICENCE 773 0- Immunogenetics Springer-Verlag 35/5(1992-03-01), 316-323 0093-7711 35:5<316 1992 35 251 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer