caa a22 4500 469038128 CHVBK 20180323132801.0 cr unu---uuuuu 170328e19920801xx s 000 0 eng 10.1007/BF00812325 doi (NATIONALLICENCE)springer-10.1007/BF00812325 Complete1H- and13C-NMR spectroscopic assignment of two pentadecapeptides by reverse C,H correlation techniques [Elektronische Daten] [Hermann Kalchhauser, Martin Kriech, Horst Ahorn, W. Sommergruber] Vollständige1H- und13C-NMR-spektroskopische Zuordnung von zwei Pentadecapeptiden mittels invers detektierter C,H-Korrelationstechniken Summary: Two oligopeptides representing a wild type and a modified version of the polyprotein cleavage region for proteinase2 A of the human rhinovirus type 2 (HRV 22 A) have been investigated using homo- and heterocorrelated 2 D NMR spectroscopy. Proton-detected C,H correlation techniques turned out to be extremely useful for sequential resonance assignment. In one case, the complete amino acid backbone could be analyzed without using NOESY spectra, thus avoiding ambiguities inherent to this method. No defined tertiary structure of the cleavage region could be detected in either molecule. However, one of the oligopeptides is present to a very low extent in a conformation different from therandom-coil arrangement. Springer-Verlag, 1992 Virus nationallicence Peptide nationallicence NMR nationallicence Assignment nationallicence Reverse Techniques nationallicence Conformation nationallicence Kalchhauser Hermann Department of Organic Chemistry, University of Vienna, A-1090, Wien, Austria aut Kriech Martin Department of Organic Chemistry, University of Vienna, A-1090, Wien, Austria aut Ahorn Horst Ernst-Boehringer-Institut für Arzneimittelforschung, A-1120, Wien, Austria aut Sommergruber W. Ernst-Boehringer-Institut für Arzneimittelforschung, A-1120, Wien, Austria aut Monatshefte für Chemie / Chemical Monthly Springer-Verlag 123/8-9(1992-08-01), 757-768 0026-9247 123:8-9<757 1992 123 706 https://doi.org/10.1007/BF00812325 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00812325 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kalchhauser Hermann Department of Organic Chemistry, University of Vienna, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Kriech Martin Department of Organic Chemistry, University of Vienna, A-1090, Wien, Austria aut NATIONALLICENCE 700 1- Ahorn Horst Ernst-Boehringer-Institut für Arzneimittelforschung, A-1120, Wien, Austria aut NATIONALLICENCE 700 1- Sommergruber W. Ernst-Boehringer-Institut für Arzneimittelforschung, A-1120, Wien, Austria aut NATIONALLICENCE 773 0- Monatshefte für Chemie / Chemical Monthly Springer-Verlag 123/8-9(1992-08-01), 757-768 0026-9247 123:8-9<757 1992 123 706 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer