caa a22 4500 46903937X CHVBK 20180323132807.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00810932 doi (NATIONALLICENCE)springer-10.1007/BF00810932 Model studies on protease-catalysed peptide synthesis using 9-fluorenylmethoxycarbonyl protected amino acid derivatives [Elektronische Daten] [Peter Kuhl, Simone Säuberlich, Hans-Dieter Jakubke] Modelluntersuchungen zur Protease-katalysierten Peptidsynthese unter Verwendung 9-Fluorenylmethoxycarbonyl-geschützter Aminosäurederivate Summary: Fmoc-Phe-OMe,Fmoc-Ala-OMe andFmoc-Gly-OH were coupled with H-Leu-NH2 under catalytic action of chymotrypsin, papain and thermolysin, respectively. The influence of different reaction media and several reaction parameters, such as reactants and enzyme concentrations as well as reaction time, on the peptide bond formation was investigated. Springer-Verlag, 1992 Enzymatic peptide synthesis nationallicence Fmoc -protected amino acid derivatives nationallicence Chymotrypsin nationallicence Papain nationallicence Thermolysin nationallicence Kuhl Peter Biosciences Division, Department of Biochemistry, Leipzig University, D-O-7010, Leipzig, Federal Republic of Germany aut Säuberlich Simone Biosciences Division, Department of Biochemistry, Leipzig University, D-O-7010, Leipzig, Federal Republic of Germany aut Jakubke Hans-Dieter Biosciences Division, Department of Biochemistry, Leipzig University, D-O-7010, Leipzig, Federal Republic of Germany aut Monatshefte für Chemie / Chemical Monthly Springer-Verlag 123/11(1992-11-01), 1015-1022 0026-9247 123:11<1015 1992 123 706 https://doi.org/10.1007/BF00810932 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00810932 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kuhl Peter Biosciences Division, Department of Biochemistry, Leipzig University, D-O-7010, Leipzig, Federal Republic of Germany aut NATIONALLICENCE 700 1- Säuberlich Simone Biosciences Division, Department of Biochemistry, Leipzig University, D-O-7010, Leipzig, Federal Republic of Germany aut NATIONALLICENCE 700 1- Jakubke Hans-Dieter Biosciences Division, Department of Biochemistry, Leipzig University, D-O-7010, Leipzig, Federal Republic of Germany aut NATIONALLICENCE 773 0- Monatshefte für Chemie / Chemical Monthly Springer-Verlag 123/11(1992-11-01), 1015-1022 0026-9247 123:11<1015 1992 123 706 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer