caa a22 4500 469049243 CHVBK 20180323132825.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF00175979 doi (NATIONALLICENCE)springer-10.1007/BF00175979 Influence of exercise-induced bronchoconstriction on refractoriness [Elektronische Daten] [Dennis Nowak, Rudolf Jörres, Helgo Magnussen] This study determined if the degree of exercise-induced refractoriness is determined by the degree of exercise-induced bronchoconstriction. In 12 patients with exercise-induced asthma (mean [SEM] age 27 [3] years) we performed 2 pairs of exercise challenges 45 min apart at different work loads on 2 days. Mean (SEM) total respiratory heat loss during low and high work loads was 3.4 (0.2) and 5.1 (0.4) kcal, respectively. After the first and second exercise challenge at low work loads, mean (SEM) SRaw increased by 107 (15) and 73 (16)% (n.s.), as compared to 361 (40) and 98 (25)% at high work loads (p < 0.005). We found a correlation between the initial airways response and refractoriness (r = 0.58, p < 0.005) and conclude that the degree of refractoriness after exercise-induced bronchoconstriction is in part dependent on the severity of exercise-induced bronchoconstriction. Springer-Verlag, 1992 Asthma nationallicence exercise-induced nationallicence Bronchoconstriction nationallicence Refractoriness nationallicence Nowak Dennis Krankenhaus Großhansdorf, Zentrum für Pneumologie und Thoraxchirurgie, Wöhrendamm 80, D-2070, Großhansdorf, Germany aut Jörres Rudolf Krankenhaus Großhansdorf, Zentrum für Pneumologie und Thoraxchirurgie, Wöhrendamm 80, D-2070, Großhansdorf, Germany aut Magnussen Helgo Krankenhaus Großhansdorf, Zentrum für Pneumologie und Thoraxchirurgie, Wöhrendamm 80, D-2070, Großhansdorf, Germany aut Lung Springer-Verlag 170/2(1992-03-01), 75-84 0341-2040 170:2<75 1992 170 408 https://doi.org/10.1007/BF00175979 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00175979 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nowak Dennis Krankenhaus Großhansdorf, Zentrum für Pneumologie und Thoraxchirurgie, Wöhrendamm 80, D-2070, Großhansdorf, Germany aut NATIONALLICENCE 700 1- Jörres Rudolf Krankenhaus Großhansdorf, Zentrum für Pneumologie und Thoraxchirurgie, Wöhrendamm 80, D-2070, Großhansdorf, Germany aut NATIONALLICENCE 700 1- Magnussen Helgo Krankenhaus Großhansdorf, Zentrum für Pneumologie und Thoraxchirurgie, Wöhrendamm 80, D-2070, Großhansdorf, Germany aut NATIONALLICENCE 773 0- Lung Springer-Verlag 170/2(1992-03-01), 75-84 0341-2040 170:2<75 1992 170 408 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer