caa a22 4500 469049812 CHVBK 20180323132827.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF02974068 doi (NATIONALLICENCE)springer-10.1007/BF02974068 Paik Young-Sook Department of Chemistry, Kyung Hee University, 449-701, Suwon aut Complex formation of tunichrome Mm-2 with ferrous and ferric ions [Elektronische Daten] [Young-Sook Paik] Mm-2, a tunichrome from iron-accumulating tunicate,Molgular manhattensis, was synthesized and measured by uv/visible spectrophotometer for the complex formation with iron. Several portions (0.1-0.5 equivalents) of freshly prepared degassed aqueous ferrous chloride solution were added to Mn-2 in 10 mM degassed sodium phosphate buffer, pH 7.0. Absorption maximum at 325 nm of Mm-2 was disappeared upon addition of ferrous chloride with concomitant appearance of absorption peaks at 365 nm and about 590 nm. Stoichiometry of Mm-2/iron complex was estimated as about 2.5∶1. The uv/visible spectrum of free Mm-2 in which hydroxyl groups were protected witht-butyldimethylsilyl (TBDMS) groups was not changed upon addition of ferrous chloride. This result suggests that catechol moieties of tunichrome Mm-2 play an important role for the complexation reaction. The addition of ferric chloride showed an essentially identical final absorption spectrum as in ferrous chloride case except that ferric chloride should be added in excess. These preliminary results support that tunichrome Mm-2 has an ability to chelate iron and to reduce Fe(III) to Fe(II). The Pharmaceutical Society of Korea, 1992 Tunichrome nationallicence Mm-2 nationallicence tunicate nationallicence iron nationallicence complexation nationallicence ferrous and ferric ions nationallicence catechol nationallicence Archives of Pharmacal Research Pharmaceutical Society of Korea 15/3(1992-09-01), 269-271 0253-6269 15:3<269 1992 15 12272 https://doi.org/10.1007/BF02974068 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974068 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Paik Young-Sook Department of Chemistry, Kyung Hee University, 449-701, Suwon aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/3(1992-09-01), 269-271 0253-6269 15:3<269 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer