caa a22 4500 469049855 CHVBK 20180323132827.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF02974055 doi (NATIONALLICENCE)springer-10.1007/BF02974055 Relative bioavailability studies on two tablet preparations of ofloxacin [Elektronische Daten] [Ashok Shakya, Naresh Talwar, Jayant Karajgi, Akhlesh Singhai] Comparative bioavailability of two tablet dosage forms of ofloxacin (either as Hoechst (India) or Ranbaxy preparation) was investigated. In a randomized cross-over study, eight healthy human volunteers received single 200 mg dose of film coated ofloxacin in fasting state. The concentrations of ofloxacin in the collected saliva and serum samples were measured by high performance liquid chromatography. No significant difference in bioavailability of both preparations was judged from various serum and saliva pharmacokinetic parameters such as peak concentration, time to peak concentration and area under the curves. Intersubject variation was also found to be insignificant. The Pharmaceutical Society of Korea, 1992 Ofloxacin nationallicence comparative bioavailability nationallicence Shakya Ashok aut Talwar Naresh aut Karajgi Jayant aut Singhai Akhlesh aut Archives of Pharmacal Research Pharmaceutical Society of Korea 15/3(1992-09-01), 208-210 0253-6269 15:3<208 1992 15 12272 https://doi.org/10.1007/BF02974055 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974055 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shakya Ashok aut NATIONALLICENCE 700 1- Talwar Naresh aut NATIONALLICENCE 700 1- Karajgi Jayant aut NATIONALLICENCE 700 1- Singhai Akhlesh aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/3(1992-09-01), 208-210 0253-6269 15:3<208 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer