caa a22 4500 469049987 CHVBK 20180323132828.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02974118 doi (NATIONALLICENCE)springer-10.1007/BF02974118 Immunostimulating activity of Phellinus linteus extracts to B-lymphocyte [Elektronische Daten] [Goo Oh, Sang Han, Hwan Kim, Man Han, Ick Yoo] Phellinus linteus was examined on its immunostimulating activities using anin vitro immunization and plaque forming cell assay. When lymphocytes were exposed to the extract ofPhellinus linteus, the number of antibody forming cell was increased. Inin vitro plaque forming cell assay, the immunostimulating effect was about 4.8 and 5.0 times of unimmunized control in polyclonal and T-independent antibody response, respectively. Especially,Phellinus linteus significantly increased the antigenicity of TNP-LPS used as T-independent antigen. ButPhellinus linteus did not show a mitogenic effect on B-lymphocytes. These results suggest that immunostimulating activity ofPhillinus linteus might be associated with a funtional stimulation of B-lymphocyte involved in humoral immune responses. The Pharmaceutical Society of Korea, 1992 Phellinus linteus nationallicence antibody-forming cell polyclonal antigen nationallicence T-independent antigenic effect nationallicence Oh Goo Daeduk Science Town, 305-606, Taejeon, Korea aut Han Sang Daeduk Science Town, 305-606, Taejeon, Korea aut Kim Hwan Daeduk Science Town, 305-606, Taejeon, Korea aut Han Man Hankook Sin Yak Pharm. Manufac. Co., Ltd., Seo-ku, 302-234, Taejeon, Korea aut Yoo Ick Daeduk Science Town, 305-606, Taejeon, Korea aut Archives of Pharmacal Research Pharmaceutical Society of Korea 15/4(1992-12-01), 379-381 0253-6269 15:4<379 1992 15 12272 https://doi.org/10.1007/BF02974118 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974118 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Oh Goo Daeduk Science Town, 305-606, Taejeon, Korea aut NATIONALLICENCE 700 1- Han Sang Daeduk Science Town, 305-606, Taejeon, Korea aut NATIONALLICENCE 700 1- Kim Hwan Daeduk Science Town, 305-606, Taejeon, Korea aut NATIONALLICENCE 700 1- Han Man Hankook Sin Yak Pharm. Manufac. Co., Ltd., Seo-ku, 302-234, Taejeon, Korea aut NATIONALLICENCE 700 1- Yoo Ick Daeduk Science Town, 305-606, Taejeon, Korea aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/4(1992-12-01), 379-381 0253-6269 15:4<379 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer